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Primary cutaneous malignancies are among the most commonly diagnosed types of cancer worldwide. We aimed to examine the incidence and 5‐year survival rates of all types of primary cutaneous malignancies in the Korean population. Data from the Korean Nationwide Cancer Registry from 1999 to 2019 were analyzed. The crude incidence rates, age‐standardized incidence rates, and 5‐year relative survival rates of each type of skin cancer were calculated. A total of 89 965 patients were diagnosed with primary cutaneous malignancies, which was a 7‐fold increase from 1999 to 2019. The age‐standardized incidence rates increased 3.4‐fold in basal cell carcinoma (3.7/100 000 person‐years), 2.0‐fold in squamous cell carcinoma (1.6/100 000 person‐years), 12.0‐fold in Bowen disease (1.2/100 000 person‐years), and 1.8‐fold in malignant melanoma (0.7/10 000 person‐years) in 2019. Average annual percentage changes in age‐standardized incidence rates were statistically significant in basal cell carcinoma (15.8%), Bowen disease (5.8%), squamous cell carcinoma (5.1%), malignant melanoma (1.2%), melanoma in situ (1.1%), dermatofibrosarcoma protuberans (1.2%), mycosis fungoides (0.5%), primary cutaneous CD30+ T‐cell proliferations (0.5%), adnexal and skin appendage carcinoma (0.4%), extramammary Paget's disease (0.2%), and Merkel cell carcinoma (0.2%). The 5‐year relative survival rates were the highest in basal cell carcinoma (103.3%), followed by dermatofibrosarcoma protuberans (99.7%) and mycosis fungoides (96.6%), and lowest in angiosarcoma (24.7%). The 5‐year relative survival rates steadily increased in extramammary Paget's disease (23.6%), cutaneous B‐cell lymphoma (21.3%), mycosis fungoides (20.2%), extranodal NK/T‐cell lymphoma, nasal type (18.1%), and malignant melanoma (16.1%) from 1996–2000 to 2015–2019. Most primary cutaneous malignancies have increased in incidence and survival rates in the Korean population, but to varying extents depending on the type of skin cancer. [ABSTRACT FROM AUTHOR]

Various patterns of nail plate destruction are common features in subungual melanoma ( SUM), but there has been no reports regarding their clinical significance according to the pattern of nail plate destruction in terms of tumor thickness. We tried to find a relationship between dermal invasion of SUM and proximal nail plate destruction ( PNPD). Clinical information of patients with SUM was reviewed retrospectively from seven dermatology training hospitals in Korea. The PNPD was defined as a visible loss of full thickness of nail plate touching the eponychium at the most proximal part of it. We evaluated whether there are correlations between patients' age, sex, location of SUM, Breslow thickness ( BT) and the presence of PNPD. Among 93 patients with SUM, 36 (38.7%) showed PNPD. Sex and BT showed significant correlations with the presence of PNPD in univariate analysis ( P < 0.05). BT, age and sex showed significant correlations with the presence of PNPD in multivariate analysis ( P < 0.05). Among them, BT showed the strongest correlation with the presence of PNPD (area under the curve, 0.722) and the cut-off value was 1.25 mm. In conclusion, we suggest that PNPD in SUM could be a possible predictor of invasiveness of more than 1.25 mm BT. [ABSTRACT FROM AUTHOR]