1. Effects of Honey Supplementation on Hepatic and Cardiovascular Disease(CVD) Marker in Streptozotocin-Induced Diabetic Rats
- Author
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Belal Mh, Shahangir Biswas, Khan Mmh, M. Khatun, M Mazibur Rahman, Munira S, Muedur Rahman M, Sohanur Rahman M, Karim Mr, Siddique Mah, M. A. Islam, Mohammad Asaduzzaman, and Mahadi Hasan
- Subjects
medicine.medical_specialty ,Very low-density lipoprotein ,Antioxidant ,medicine.diagnostic_test ,business.industry ,Cholesterol ,medicine.medical_treatment ,fungi ,Intraperitoneal injection ,Cholic acid ,food and beverages ,Streptozotocin ,medicine.disease ,chemistry.chemical_compound ,Endocrinology ,chemistry ,Internal medicine ,Diabetes mellitus ,Medicine ,business ,Lipid profile ,medicine.drug - Abstract
Introduction: Honey is not just a sweetener it is also a nature’s gift to mankind. Natural honey has various ingredients in it that contribute to its incredible properties. Honey contain health-beneficial effects such as gastro protective, hepatoprotective, reproductive, hypoglycemic, antioxidant, antibacterial, and anti-inflammatory effects. For that reason, honey could be considered as a potential remedy for diabetes as well as Cardiovascular Disease(CVD). The objective of this study was to determine the phytochemical activity of honey and its role on hypoglycemic and hypolipidemic condition in Streptozotocin- induced diabetic rats. Material and method: The Experimental rats were divided into six groups (n=6). Diabetes Mellitus (DM) was induced by single intraperitoneal injection (65 mg/kg BW) of freshly prepared Streptozotocin hydrate solution in 0.9% saline solution. Hyperlipidemic was induced by mixture of cholesterol (1.5 %) and cholic acid (0.5%) with diet of rats. At the end of the treatment, the blood glucose level and lipid profile was measured by using commercial kits. Result: Honey bee-treatment significantly decreases blood glucose level in diabetic rats. TC, TG, LDL, VLDL are significantly (p
- Published
- 2015
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