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The Arctic region is very sensitive to climate change and important in the Earth’s climate system. However, proxy datasets for Arctic climate are unevenly distributed and especially scarce for Svalbard because glaciers during the Little Ice Age, the most extensive in the Holocene, destroyed large quantities of sediment records in Svalbard. Fortunately, palaeo-notch sediments could withstand glaciers and be well-preserved after deposition. In this study, we reconstructed a mid-to-late Holocene record of climate changes in a palaeo-notch sediment sequence from London Island. Multiple weathering indices were determined, they all showed consistent weathering conditions in the study area, and they were closely linked to climate changes. Total organic carbon (TOC) and total nitrogen (TN) were also determined, and their variation profiles were similar to those of weathering indices. The climate change record in our sediment sequence is consistent with ice rafting record from North Atlantic and glacier activity from Greenland, Iceland and Svalbard, and four cold periods are clearly present. Our study provides a relatively long-term climate change record for climate conditions from mid-to-late Holocene in Svalbard. [ABSTRACT FROM AUTHOR]