1. Synthesis of perovskite-type SrTiO3 nanoparticles for sensitive electrochemical biosensing applications.
- Author
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Dai, Hua, Zhong, Yihong, Wu, Xinyue, Hu, Ruixuan, Wang, Lei, Zhang, Yongcai, Fan, Guokang, Hu, Xiaoya, Li, Juan, and Yang, Zhanjun
- Subjects
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PEROVSKITE , *ELECTROCHEMICAL sensors , *BIOSENSORS , *GLUCOSE oxidase , *STRONTIUM titanate , *NANOPARTICLES - Abstract
In this work, SrTiO 3 nanoparticles (SrTiO 3 NPs), a novel and effective perovskite-type material, are synthesized to modify electrode for the development of sensitive enzymatic electrochemical biosensor applications. The electrochemical behavior of glucose oxidase (GOx) immobilized on SrTiO 3 NPs-modified glassy carbon electrode is investigated. Scanning electron microscopy and cyclic voltammetry are used to characterize the morphology and assay property of different modified electrodes. Results illustrate that SrTiO 3 NPs possess large surface area and apparently enhance the direct electron transfer between GOx and modified electrode. The SrTiO 3 NPs-based enzyme biosensor shows a high sensitivity of 15.6 mA·M − 1 ·cm − 2 , wide linear range from 0.01 mM to 1.2 mM, and a low detection limit of 3 μM (S/N = 3). Furthermore, the resultant glucose biosensor has excellent selectivity, acceptable repeatability, practicality and stability. The perovskite SrTiO 3 NPs provide a very attractive and potential electrode material to develop electrochemical biosensors. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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