1. Residue analysis and dietary risk assessment of tebuconazole in loquat and sugarcane after open-field application in China.
- Author
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Chen, Wuying, Li, Kailong, Chen, Ang, Luo, Xiangwen, Xiong, Hao, Song, Zengshou, Zhang, Ying, and Liu, Yong
- Subjects
LOQUAT ,SUGARCANE ,LIQUID chromatography-mass spectrometry ,TEBUCONAZOLE ,RISK assessment ,SOLID phase extraction - Abstract
Tebuconazole is an effective but potentially carcinogenic fungicide. Tebuconazole residues in loquat and sugarcane were investigated, together with an analysis of their dietary risk. Solid-phase extraction and high-performance liquid chromatography-tandem mass spectrometry showed fortified recoveries of 87% to 98%, with standard deviations ≤ 6.4%. The tebuconazole residues were below 6.34 mg kg
−1 for whole loquat and 0.80 mg kg−1 for sugarcane. Based on the final residue test, the chronic hazard index was 90.74% in whole loquat and sugarcane, while the acute hazard index ranged from 66.32% to 109.49% for loquat and 33.37% to 76.93% for sugarcane. The assessment of potential dietary risk showed that while loquats may represent an acute risk to human health, whereas sugarcane consumption was safe. A 21-day pre-harvest interval is proposed to comply with maximum residue limit regulations and the observed risks when using 430 g/L tebuconazole for treating sugarcane. These findings offer guidance for tebuconazole formulation and use. [ABSTRACT FROM AUTHOR]- Published
- 2022
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