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1. Adefovir dipivoxil monotherapy is a sufficiently effective treatment modality for Japanese patients with lamivudine-resistant chronic hepatitis B.

Author

Sato, Ken, Takagi, Hitoshi, Kakizaki, Satoru, Sohara, Naondo, and Mori, Masatomo

Subjects
HEPATITIS B virus, DRUG resistance, ALANINE aminotransferase, HEPATITIS B, PATIENTS
Abstract

The article presents a study to evaluate the efficacy of adefovir dipivoxil monotherapy for Japanese patients with lamivudine-resistant chronic hepatitis B. The study found that the alanine aminotransferase level in all the patients under observation decreased and normalized in 67 percent patients at 48 weeks. It was also seen that the incidence of adefovir dipivoxil-related hepatitis B virus mutations and drug resistance is extremely low.

Published
2006
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