Search

Background: Krukenberg tumour (KT) is clinically defined as any ovarian metastatic carcinoma derived from a primary malignancy (usually from the gastrointestinal tract). Our aim was to analyse the incidence, demographic profile, clinical features, management and survival of patients with KTs from gastrointestinal tract malignancies at our centre., Methods: This was a retrospective analysis data at our centre between Jan 2015 and Dec 2017., Results: A total of 8 patients of KTs (2 from gastric and 6 from colorectal cancers) were observed with an incidence of 0.66% in gastric and 2.90% in colorectal cancers. The mean age of all the patients was 40 years (44 in gastric and 39 in colorectal group) and most of them (5 out of 8) occurred in premenopausal women. They were also most commonly bilateral (6 out of 8) and synchronous (6 out of 8). Surgical debulking was possible in 7 patients and all patients underwent systemic chemotherapy. Interestingly, 4 patients in the colorectal KT group with metastasis limited to ovary alone managed by surgical debulking and chemotherapy had a significantly higher 1-year survival compared to the others with peritoneal disease are alive at an average of 14.5 months., Conclusions: The incidence of KTs from colorectal cancers is on the rise. KTs from colorectal cancers and KTs without peritoneal metastases have a better prognosis showing significantly higher 1-year survival rates following complete surgical resection and systemic chemotherapy., Competing Interests: Conflicts of Interest: The authors have no conflicts of interest to declare.