1. The first-round results of a population-based cohort study of HPV testing in Japanese cervical cancer screening: baseline characteristics, screening results, and referral rate
- Author
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Daisuke Aoki, Kiyoshi Ito, Kumiko Saika, Hirokazu Takahashi, Kanako Kono, Eiko Saitoh Aoki, Etsuko Miyagi, Hiroshi Saito, Tohru Morisada, and Tomio Nakayama
- Subjects
medicine.medical_specialty ,Referral ,Population ,Uterine Cervical Neoplasms ,Alphapapillomavirus ,Cervical cancer screening ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,Japan ,Pregnancy ,Cytology ,Cancer screening ,Humans ,Medicine ,education ,Papillomaviridae ,Referral and Consultation ,Early Detection of Cancer ,Vaginal Smears ,Cervical cancer ,education.field_of_study ,030219 obstetrics & reproductive medicine ,business.industry ,Obstetrics ,Papillomavirus Infections ,Obstetrics and Gynecology ,General Medicine ,medicine.disease ,Hpv testing ,Editorial ,Oncology ,Colposcopy ,030220 oncology & carcinogenesis ,Female ,business ,Cohort study - Abstract
OBJECTIVE In 2013, a cohort study aimed to clarify the positive and negative effects of introducing the human papillomavirus (HPV) testing for population-based cervical cancer screening has been launched in Japan. This study included four screenings during the subsequent 7-year follow-up period. We aim to describe the results of the first round of this study on cervical cancer screening here. METHODS This study began in September 2013 with recruitment completed in March 2016. Women aged 30-49 years were divided into 2 groups: those who received uterine cervical cytology alone in the first year (control group), or those who received a combination of cytology and HPV testing (intervention group), based on their age. After first screening, women with positive result of cytology or positive HPV test required referral. We summarized the results of the first round of cervical cancer screening. RESULTS Of the 25,074 women who were eligible for the study, 13,845 women (55.2%) were screened with cytology alone; 11,229 women (44.8%) received a combination of cytology and HPV testing. After screening, 407 women (2.9%) in the control group and 1,003 women (8.9%) in the intervention group required referral, respectively. Adding HPV testing increased referral rate significantly (p
- Published
- 2021