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Endocrine disrupting chemicals (EDCs) can interfere with the normal function of endocrine system, posing serious risk to human health. The monitoring of EDCs in foods is of great importance to ensure food security. Herein, a cyano and ionic dual-functionalized hypercrosslinked porous polymer (CN-iHCP) was designed and prepared for the first time through hyper-crosslink of 1-(4-cyanophenyl)imidazole and 1,4-bis(chloromethyl)benzene. The adsorption mechanism mainly involves electrostatic interaction, hydrogen bonding and π-π stacking interaction. A sensitive analytical method for simultaneous detection of the four phenolic EDCs was established by coupled CN-iHCP based solid-phase extraction with high performance liquid chromatography. Under optimal conditions, the target EDCs exhibited good linearity with coefficient r > 0.993 and high enrichment factors of 164–243. The detection limits (S/N = 3) of EDCs were 0.20–0.50 ng mL−1 for milk sample. The extraction recoveries for the spiked milk samples were in the range of 85.5%− 116.0%. This work not only highlights the CN-iHCP as a promising adsorbent to efficiently enrich EDCs and other pollutants, but also provides a new strategy for the functionalization of HCP for wide applications. [Display omitted] • Cyano and ionic dual-functional porous polymer (CN-iHCP) was synthesized. • CN-iHCP gave a large adsorption capacity and fast adsorption kinetics for EDCs. • Adsorption mechanism involved electrostatic force, hydrogen bond and π-π stacking. • A CN-iHCP based HPLC method was developed for sensitive detection of EDCs in milk. [ABSTRACT FROM AUTHOR]