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Introduction: As a result of research conducted globally, experts continue to extensively study the long-term consequences that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections can have on patients, as well as the factors contributing to severe outcomes. The aim of this study was to investigate the values of basic biochemical and hematological parameters in patients with fatal outcomes of SARS-CoV-2 infection, as well as to determine the combination of hematological and biochemical parameters that contribute to the progression of SARS-CoV-2 infection. The examined parameters were correlated with the age and gender distribution of patients with fatal outcomes from the SARS-CoV-2 infection. Methods: The study represents a retrospective study of patients hospitalized at the Cantonal Hospital Zenica from February to April 2021, focusing on the biochemical and hematological parameters of subjects with confirmed presence of the SARS-CoV-2 virus using the reverse transcription-polymerase chain reaction methods who were hospitalized at the Cantonal Hospital Zenica. Results: Of the 250 deceased subjects in the sample, females comprised the relative majority at 53.6%. Among the examined parameters, hemoglobin, mean corpuscular hemoglobin (MCH), and MCH were significantly lower in females compared to males, while males had significantly higher values of urea, creatinine, and troponin. The average age of the patients was 74 years, and with aging, the values of erythrocytes, hemoglobin, and troponin increased. Troponin showed a statistically significant positive correlation with age, as well as with urea and creatinine. Conclusion: We can conclude that hemoglobin, urea, creatinine, and troponin are parameters that can be considered to contribute to the progression of SARS-CoV-2 infection. These parameters can be useful for assessing disease severity and prognosis in patients infected with the SARS-CoV-2 virus.

Introduction: Menopause is the absence of menses in the period longer that one year. It is widely accepted that menopause leads to changes in hormonal status, metabolism and lipid profi le. The aim of this study wasto analyze the infl uence of menopause on the concentrations of lipids, lipoproteins and also the influence of body mass index (BMI) and waist-hip ratio (WHR) on lipid profi le in post-menopausal women.Methods: Sixty post-menopausal women of average age of 52.82 years were compared to a group of 34 pre-menopausal women average age of 47.92 years.Results: Post-menopausal women had higher, but non signifi cant (p>0.05) concentrations of total cholesterol, very low density lipoproteins (VLDL), low density lipoproteins (LDL) and triglycerides than pre-menopausal women. The concentration of high density lipoproteins (HDL) was significantly lower in post-menopausal women than pre-menopausal (pbut without signifi cance (p>0.05). There was no difference between body mass index (BMI) and waste-hip ratio (WHR), but the WHR has shown as a signifi cant predictor of the LDL and cholesterol concentrations inpost-menopausal women.Conclusion: We can conclude that menopause leads to changes in lipid profi le by lowering of HDL and increasing the levels of apolipoprotein B, that increases the risk for cardiovascular disease. The WHR is thesignifi cant predictor of cardiovascular risk in post-menopausal women.

Introduction: Menopause is the absence of menses in the period longer that one year. It is widely accepted that menopause leads to changes in hormonal status, metabolism and lipid profi le. The aim of this study was to analyze the infl uence of menopause on the concentrations of lipids, lipoproteins and also the influence of body mass index (BMI) and waist-hip ratio (WHR) on lipid profi le in post-menopausal women. Methods: Sixty post-menopausal women of average age of 52.82 years were compared to a group of 34 pre-menopausal women average age of 47.92 years. Results: Post-menopausal women had higher, but non signifi cant (p>0.05) concentrations of total cholesterol, very low density lipoproteins (VLDL), low density lipoproteins (LDL) and triglycerides than pre-menopausal women. The concentration of high density lipoproteins (HDL) was significantly lower in post-menopausal women than pre-menopausal (p0.05). There was no difference between body mass index (BMI) and waste-hip ratio (WHR), but the WHR has shown as a signifi cant predictor of the LDL and cholesterol concentrations in post-menopausal women. Conclusion: We can conclude that menopause leads to changes in lipid profi le by lowering of HDL and increasing the levels of apolipoprotein B, that increases the risk for cardiovascular disease. The WHR is the signifi cant predictor of cardiovascular risk in post-menopausal women.