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Your search keyword '"Dekker, Jacqueline M."' showing total 13 results
Start Over Author "Dekker, Jacqueline M." Journal journal of hypertension
13 results on '"Dekker, Jacqueline M."'

1. Real-world evidence of suboptimal blood pressure control in patients with type 2 diabetes

Author

Walraven, Iris, primary, Mast, M. Ruth, additional, Hoekstra, Trynke, additional, Jansen, Aaltje P.D., additional, Rauh, Simone P., additional, Rutters, Femke R., additional, van der Heijden, Amber A.W.A., additional, Elders, Petra J.M., additional, Moll, Annette C., additional, Polak, Bettine C.P., additional, Dekker, Jacqueline M., additional, and Nijpels, Giel, additional

Published
2015
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5. The association between the −374T/A polymorphism of the receptor for advanced glycation endproducts gene and blood pressure and arterial stiffness is modified by glucose metabolism status: the Hoorn and CoDAM studies

Author

Engelen, Lian, primary, Ferreira, Isabel, additional, Gaens, Katrien HJ, additional, Henry, Ronald MA, additional, Dekker, Jacqueline M, additional, Nijpels, Giel, additional, Heine, Robert J, additional, 't Hart, Leen M, additional, van Greevenbroek, Marleen MJ, additional, van der Kallen, Carla JH, additional, Blaak, Ellen E, additional, Feskens, Edith JM, additional, ten Cate, Hugo, additional, Stehouwer, Coen DA, additional, and Schalkwijk, Casper G, additional

Published
2010
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6. Polymorphisms in glyoxalase 1 gene are not associated with vascular complications: the Hoorn and CoDAM studies

Author

Engelen, Lian, primary, Ferreira, Isabel, additional, Brouwers, Olaf, additional, Henry, Ronald MA, additional, Dekker, Jacqueline M, additional, Nijpels, Giel, additional, Heine, Robert J, additional, van Greevenbroek, Marleen MJ, additional, van der Kallen, Carla JH, additional, Blaak, Ellen E, additional, Feskens, Edith JM, additional, ten Cate, Hugo, additional, Stehouwer, Coen DA, additional, and Schalkwijk, Casper G, additional

Published
2009
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10. L-Homoarginine and L-arginine are antagonistically related to blood pressure in an elderly population

Author

Zwan, Leonard P. van der, Davids, Mariska, Scheffer, Peter G., Dekker, Jacqueline M., Stehouwer, Coen D.A., and Teerlink, Tom

Abstract

Production of nitric oxide by the vascular endothelium is crucial for the maintenance of vascular tone, an important determinant of blood pressure. L-Arginine and its homolog L-homoarginine are competitive substrates of nitric oxide synthase (NOS), whereas asymmetric dimethylarginine (ADMA) is a NOS inhibitor. We evaluated the relationships between physiological levels of these amino acids and blood pressure.

Published
2013
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11. Low-grade inflammation, but not endothelial dysfunction, is associated with greater carotid stiffness in the elderly

Author

Bussel, Bas C.T. van, Henry, Ronald M.A., Schalkwijk, Casper G., Dekker, Jacqueline M., Nijpels, Giel, and Stehouwer, Coen D.A.

Abstract

Biomarkers of low-grade inflammation and endothelial dysfunction are associated with cardiovascular disease. Arterial stiffening may be a mechanism through which low-grade inflammation and (or) endothelial dysfunction lead to cardiovascular disease. Therefore, we investigated whether low-grade inflammation and endothelial dysfunction were associated with greater carotid stiffness in a population-based cohort of elderly individuals.

Published
2012
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12. Change in common carotid artery diameter distensibility and compliance in subjects with a recent history of impaired glucose tolerance

Author

Dijk, Robert A.J.M. van, Nijpels, Giel, Twisk, Jos W.R., Steyn, Mieke, Dekker, Jacqueline M., Heine, Robert J., Donker, Ab J.M., and Stehouwer, Coen D.A.

Abstract

To assess the development of common carotid artery properties (diameter, distensibility and compliance) in a cohort of 140 subjects (mean age 65.8 years, SD 7.5 years) originally diagnosed as impaired glucose tolerant in a population-based study, and to explore determinants of changes observed.

Published
2000

13. The association between the -374T/A polymorphism of the receptor for advanced glycation endproducts gene and blood pressure and arterial stiffness is modified by glucose metabolism status: the Hoorn and CoDAM studies.

Author

Engelen L, Ferreira I, Gaens KH, Henry RM, Dekker JM, Nijpels G, Heine RJ, 't Hart LM, van Greevenbroek MM, van der Kallen CJ, Blaak EE, Feskens EJ, Ten Cate H, Stehouwer CD, and Schalkwijk CG

Subjects
Aged, Atherosclerosis etiology, Atherosclerosis genetics, Atherosclerosis physiopathology, Base Sequence, Cardiovascular Diseases etiology, Cardiovascular Diseases genetics, Cardiovascular Diseases physiopathology, Cohort Studies, DNA Primers genetics, Diabetes Mellitus, Type 2 genetics, Diabetes Mellitus, Type 2 physiopathology, Female, Haplotypes, Humans, Male, Middle Aged, Netherlands, Receptor for Advanced Glycation End Products, Risk Factors, Blood Pressure genetics, Glucose metabolism, Polymorphism, Single Nucleotide, Receptors, Immunologic genetics, Vascular Resistance genetics
Abstract

Objectives: Receptor for advanced glycation endproducts (RAGE)-ligand interaction may lead to vascular complications. Genetic variation in RAGE has been shown to alter expression, activity of RAGE or both. We, therefore, investigated whether RAGE single-nucleotide polymorphisms (SNPs) and haplotypes were associated with vascular disease., Methods: Nine tag SNPs that cover the common RAGE gene variation were genotyped in 1291 individuals from two Dutch population-based cohort studies, aged 64.5 +/- 8.6 years, with normal glucose metabolism (44%), impaired glucose metabolism (23%) or type 2 diabetes mellitus (33%). We used multiple regression analyses to compare prevalent cardiovascular disease and markers of atherosclerosis, blood pressure and arterial stiffness across genotypes, and examine effect modification by glucose metabolism status., Results: In unstratified analyses, no consistent associations between RAGE SNPs and prevalent cardiovascular disease and markers of atherosclerosis were found. However, the AA genotype of SNP rs1800624 (-374T/A) was consistently associated with lower SBP [-5.0 mmHg (95% confidence interval -10.4 to 0.3)] and DBP [-4.2 (-7.2 to -1.3)], pulse pressure [-0.8 (-5.0 to 3.4)] as well as with less arterial stiffness [-0.56 SD (-1.04 to -0.09)] in individuals with normal glucose metabolism, but with higher SBP [6.2 (0.9-11.5)], DBP [2.1 (-0.7 to 5.0)] and pulse pressure [4.1 (-0.2 to 8.4)] in individuals with impaired glucose metabolism or type 2 diabetes mellitus (P for interaction

Published
2010
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