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Your search keyword '"Guarino, L."' showing total 15 results
Start Over Author "Guarino, L." Journal journal of hypertension
15 results on '"Guarino, L."'

8. PP.42.07

Author

Guarino, L., primary, Geraci, G., additional, Arsena, R., additional, Vaccaro, F., additional, Guarneri, M., additional, Scazzone, C., additional, Mulé, G., additional, and Cottone, S., additional

Published
2015
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9. PP.42.06

Author

Guglielmo, C., primary, Cottone, S., additional, Guarino, L., additional, Arsena, R., additional, Scazzone, C., additional, Tornese, F., additional, Guarneri, M., additional, Bono, A., additional, and Mulé, G., additional

Published
2015
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14. [PP.07.19] ASSOCIATION OF MAXIMUM SPEED OF BLOOD PRESSURE RISE DURING 24-H ABPM WITH SUBCLINICAL RENAL DAMAGE IN ESSENTIAL HYPERTENSION

Author

Francesca Gervasi, Vaccaro F, Santina Cottone, Giuseppe Mulè, L. Guarino, R. Salemi, T. Viola, Marco Guarneri, Maria Giovanna Vario, Claudia Cusumano, Mule, G., Gervasi, F., Vario, M., Cusumano, C., Salemi, R., Guarino, L., Guarneri, M., Vaccaro, F., Viola, T., and Cottone, S.

Subjects
Arterial hypertension, Blood pressure variability, medicine.medical_specialty, Settore MED/09 - Medicina Interna, Physiology, business.industry, Renal damage, Ambulatory blood pressure, Essential hypertension, medicine.disease, Renal dysfunction, Blood pressure rise, Internal medicine, Internal Medicine, Cardiology, Medicine, Cardiology and Cardiovascular Medicine, business, Subclinical infection
Abstract

Objective: Experimental studies documented that the mechanical injury of intravascular pressure on the vessel wall, which results in vascular remodelling and atherosclerosis, may be more closely associated to oscillatory than to steady laminar shear stress This suggests that the hypertensive patient's prognosis may depend not only on average BP level but also on the degree and rate of BP variation. Little is known about the relationships between early renal abnormalities and the rate of BP changes assessed by intermittent 24-h ambulatory BP monitoring (ABPM). Our study was aimed to analyse the relationships between subclinical renal damage (SRD), defined as the presence of microalbuminuria or an estimated glomerular filtration rate (eGFR) between 30-60 ml/min/1.73 m2 and the maximum speed of BP rise (Max Slope BP) during a 24-h BP recording Design and method: The study population consisted of 389 untreated essential hypertensives (mean age: 49 +/- 13 years; males 58%), which underwent 24-h ABPM, 24-h albumin excretion rate (AER) measurement and GFR estimation, using the CKD-EPI equation. The Max Slope BP was calculated as the first derivative of the curve obtained by fitting partial Fourier series to raw BP data recorded by discontinuous 24-h ABPM. Results: The Max Slope of systolic BP (SBP) was higher in subjects with SRD (n = 117) than in those without SRD (n = 272) .

Published
2017
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15. [OP.2D.05] RELATIONSHIP OF OXIDATIVE STRESS WITH CARDIAC HYPERTROPHY IN HYPERTENSIVE PATIENTS

Author

L. Guarino, Santina Cottone, Emilio Nardi, Giuseppe Mulè, D. Altieri, Marco Guarneri, Giovanni Cerasola, Cottone, S., Nardi, E., Guarneri, M., Guarino, L., Altieri, D., Cerasola, G., and Mulè, G.

Subjects
Settore MED/14 - Nefrologia, medicine.medical_specialty, Settore MED/09 - Medicina Interna, Physiology, business.industry, medicine.disease_cause, LEFT VENTRICULAR HYPERTROPHY - ARTERIAL HYPERTENSION - OXIDATIVE STRESS, Settore MED/11 - Malattie Dell'Apparato Cardiovascolare, Cardiac hypertrophy, Internal medicine, Internal Medicine, medicine, Cardiology, Cardiology and Cardiovascular Medicine, business, Oxidative stress
Abstract

OBJECTIVE: Left ventricular hypertrophy is common in hypertensive patients. In these subjects increased oxidative stress has been observed. Our aim was to evaluate the association of biomarkers of both oxidative stress and inflammation with markers of cardiovascular damage in a large group of hypertensives with different stages of renal function. DESIGN AND METHOD: In 517 hypertensives we analyzed left ventricular mass indexed for body surface area, and we assayed plasma levels of 8-isoprostaglandin F2alpha and high sensitivity C reactive protein. RESULTS: Multivariate analysis carried out considering left ventricular mass as dependent variable, and including 8-isoprostaglandin F2alpha, high sensitivity C reactive protein, age, sex, body mass index, estimated glomerular filtration rate, serum glucose, (log)triglycerides, hemoglobin, pulse pressure or systolic blood pressure, mean or diastolic blood pressure, and antihypertensive treatment showed that in hypertensives plasma levels of 8-isoprostaglandin F2alpha were correlated with left ventricular mass (beta=0.269, p

Published
2016
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