Search

Purpose: The objective of the present study is to analyze scientometrically some essential patterns of the dynamic science institutionalization on breast cancer immunohistochemistry and to outline the most significant scientists, journals, scientific institutions conference proceedings in this interdisciplinary field. Material/Methods: In December 2019, a retrospective problem-oriented, title-word based search was performed in Web of Science Core Collection (WoS), MEDLINE and BIOSIS Citation Index (BIOSIS) of Web of Knowledge as well as in Scopus for 2003-2018. The following parameters were comparatively assessed: annual dynamics of publications, author’s names, journal titles, scientific institutions, and scientific forums. Results: There were 1187 publications abstracted in WoS, 776 publications abstracted in BIOSIS, 711 publications abstracted in Scopus, and 616 publications abstracted in MEDLINE. There were journal articles in 288 journals abstracted in WoS, in 234 journals abstracted in MEDLINE, in 156 journals abstracted in Scopus, and in 140 journals abstracted in BIOSIS. The most productive authors were David G. Hicks, Rohit Bhargava and Ian O. Ellis. The ‘core’ journals were Modern Pathology, Laboratory Investigation and Cancer Research. The most influential scientific institutions were the University of Texas System (USA) and the University of Texas MD Anderson Cancer Center (USA). The annual meetings of the US and Canadian Academy of Pathology and the Annual San Antonio Breast Cancer symposia were most attractive to the investigators worldwide. Conclusion:Our comprehensive results could be of interest to breast cancer researchers and clinicians from smaller countries, institutional science managers, and journal editors.

Purpose: To perform a retrospective analysis of mushroom poisonings in Varna region for 25 years (1991-2015). Mushroom poisonings account for 10.7% of hospitalizations associated with acute exogenous intoxication. Poisoning with Amanita phalloides, Amanita pantherina, Amanita muscaria and various fungi that cause only gastrointestinal symptoms are of greatest importance for the clinical toxicology in the Republic of Bulgaria. Material/Methods: Objects of the study were 1872 patients who received treatment at the Clinic for Intensive Treatment of Acute Intoxications and Toxicoallergies, Naval Hospital – Varna, Military Medical Academy, Bulgaria after eating mushrooms. Results: Patients with irritative gastroenteritis – 1703 (91%) were with the highest frequency, followed by those with Amanita phalloides intoxication - 147 (7.8%). Amanita phalloides poisonings are not common and have a low relative share to all mushroom intoxications, but they are characterized by severe course and high lethality. Poisonings with Amanita pantherina and Amanita muscaria are even less common – 22 (1.2%). Patients accepted for treatment were both male (50.5%) and female (49.5%). Patients in age between 25 and 60 years were prevalent – 1171 (62.6%). A fatal outcome was registered in only 25 patients with Amanita phalloides intoxications, which represents 17% of all patients with Amanita phalloides poisoning and 1.3% of all patients with mushroom intoxications. Conclusion: Mushroom poisonings causing irritant gastroenterocolitis and those with Amanita pantherina and Amanita muscaria have a good prognosis. Amanita phalloides intoxications are characterized by the development of life-threatening organ damages and high lethality.