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1. OKT3 and H57-597: From Discovery, to Commercialization, to the Clinic.

Author

Hogquist, Kristin A.

Subjects
*IMMUNOLOGY, *MUROMONAB-CD3, *MONOCLONAL antibodies, *CD3 antigen, *T cells, *T cell receptors, *IMMUNOGLOBULINS, *STREPTAVIDIN
Abstract

The article offers information on several papers on immunology that was published in the year 1980 and 1989. Topics discussed include the generation of muromonab CD-3 (OKT3) monoclonal antibodies (mAb) to the human T cells and CD3, the characterization of monoclonal antibodies to the murine T-cell receptorβ-chain (TCR β-chain), and the immunoglobulin (Ig)-binding properties of streptavidin and protein A.

Published
2016
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