1. The emergence of infections with community-associated methicillin resistant Staphylococcus aureus
- Author
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J.A.J.W. Kluytmans and Bram M. W. Diederen
- Subjects
Microbiology (medical) ,medicine.medical_specialty ,business.industry ,medicine.drug_class ,SCCmec ,Antibiotics ,Disease ,biochemical phenomena, metabolism, and nutrition ,bacterial infections and mycoses ,medicine.disease_cause ,Staphylococcal infections ,medicine.disease ,Methicillin-resistant Staphylococcus aureus ,Microbiology ,Infectious Diseases ,Staphylococcus aureus ,Internal medicine ,Epidemiology ,Medicine ,Infection control ,business - Abstract
Recently there have been reports indicating an increased incidence of MRSA infections, afflicting individuals with no apparent risk factors for hospital acquisition. Patients with community-associated (CA) MRSA are significantly younger and had different distributions of clinical infections compared with HA-MRSA patients. CA-MRSA infections have mostly been associated with staphylococcal strains bearing the SCCmec type IV element and PVL genes. These strains are more frequently susceptible to a variety of non-beta-lactam antibiotics. Clinicians must be aware of the wide and, in some cases, unique spectrum of disease caused by CA-MRSA. Continued emergence of MRSA in the community is a public-health problem that warrants increased vigilance in the diagnosis and management of suspected and confirmed staphylococcal infections.
- Published
- 2006
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