1. Association of Baseline Smoking Status with Long-Term Prognosis in Patients Who Underwent Percutaneous Coronary Intervention: Large Single-Center Data
- Author
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Zhan Gao, Jue Chen, Jingjing Xu, Lijian Gao, Bo Xu, Ying Song, Shubin Qiao, Huan-Huan Wang, Runlin Gao, Yuejin Yang, Jinqing Yuan, Xiao-Fang Tang, and Ru Liu
- Subjects
Male ,lcsh:Diseases of the circulatory (Cardiovascular) system ,China ,medicine.medical_specialty ,Article Subject ,medicine.medical_treatment ,Myocardial Infarction ,Hemorrhage ,Coronary Artery Disease ,Single Center ,Revascularization ,Coronary artery disease ,Percutaneous Coronary Intervention ,Internal medicine ,Myocardial Revascularization ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Myocardial infarction ,Stroke ,Smokers ,business.industry ,Proportional hazards model ,Percutaneous coronary intervention ,Non-Smokers ,Middle Aged ,Prognosis ,medicine.disease ,lcsh:RC666-701 ,Conventional PCI ,Female ,Cardiology and Cardiovascular Medicine ,business ,Research Article - Abstract
Objectives. This study analyzed a large sample to explain the association of baseline smoking state with long-term prognosis of coronary artery disease (CAD) patients who underwent percutaneous coronary intervention (PCI). Background. Data is limited up to now regarding whether smoker’s paradox exists in Chinese population. Methods. A total of 10724 consecutive cases were enrolled from January to December 2013. 2-year clinical outcomes were evaluated among current smokers and nonsmokers. Major adverse coronary event (MACCE) included all-cause death, revascularization, myocardial infarction (MI), and stroke. Results. Current smokers and nonsmokers accounted for 57.1% and 42.9%, respectively. Current smokers were presented with predominant male sex, lower age, and less comorbidities. The rates of 2-year all-cause death were not significantly different among two groups. But the rate of stroke and bleeding was significantly higher in nonsmokers than in current smokers (1.6% and 1.1%, P=0.031; 7.2% and 6.1%, P=0.019). The rate of revascularization was significantly higher in current smokers than in nonsmokers (9.1% and 8.0%, P=0.037). Multivariable Cox regression indicated that, compared with nonsmokers, current smokers were not independently associated with all endpoints (all P>0.05). Conclusions. 2-year all-cause death, MACCE, MI, revascularization, stroke, ST, and bleeding risk were similar between current smokers and nonsmokers in CAD patients undergoing PCI.
- Published
- 2019