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Your search keyword '"Dasdo Antonius Sinaga"' showing total 2 results
Start Over Author "Dasdo Antonius Sinaga" Journal journal of interventional cardiology
2 results on '"Dasdo Antonius Sinaga"'

1. Drug-Coated Balloons: A Safe and Effective Alternative to Drug-Eluting Stents in Small Vessel Coronary Artery Disease

Author

Thuzar Tint Nyein, Fahim Haider Jafary, Dasdo Antonius Sinaga, Jason Kwok Kong Loh, Alyssa Sim, Hee Hwa Ho, Timothy James Watson, Paul Jau Lueng Ong, Yau Wei Ooi, and Julian K.B. Tan

Subjects
medicine.medical_specialty, Acute coronary syndrome, business.industry, medicine.medical_treatment, Lumen (anatomy), Retrospective cohort study, 030204 cardiovascular system & hematology, Balloon, medicine.disease, Surgery, Coronary artery disease, 03 medical and health sciences, 0302 clinical medicine, Angioplasty, Diabetes mellitus, Cohort, Medicine, Radiology, Nuclear Medicine and imaging, 030212 general & internal medicine, Cardiology and Cardiovascular Medicine, business
Abstract

Background Drug-coated balloons (DCB) have been used to treat de novo small vessel coronary disease (SVD), with promising results and shorter dual antiplatelet therapy (DAPT) duration compared to drug-eluting stents (DES). We compared safety and effectiveness of the two treatments at 1 year. Methods We reviewed 3,613 angioplasty cases retrospectively from 2011 to 2013 and identified 335 patients with SVD treated with device diameter of ≤2.5 mm. DCB-only angioplasty was performed in 172 patients, whereas 163 patients were treated with second-generation DES. Results DCB patients had smaller reference vessel diameter (2.22 ± 0.30 vs. 2.44 ± 0.19 mm, P

Published
2016

2. Drug-Coated Balloons: A Safe and Effective Alternative to Drug-Eluting Stents in Small Vessel Coronary Artery Disease

Author

Dasdo Antonius, Sinaga, Hee Hwa, Ho, Timothy James, Watson, Alyssa, Sim, Thuzar Tint, Nyein, Fahim H, Jafary, Jason K K, Loh, Yau Wei, Ooi, Julian K B, Tan, and Paul J L, Ong

Subjects
Male, Singapore, Time Factors, Drug-Eluting Stents, Coronary Artery Disease, Middle Aged, Coronary Angiography, Prosthesis Design, Coronary Vessels, Coronary Restenosis, Outcome and Process Assessment, Health Care, Treatment Outcome, Humans, Female, Angioplasty, Balloon, Coronary, Aged, Retrospective Studies
Abstract

Drug-coated balloons (DCB) have been used to treat de novo small vessel coronary disease (SVD), with promising results and shorter dual antiplatelet therapy (DAPT) duration compared to drug-eluting stents (DES). We compared safety and effectiveness of the two treatments at 1 year.We reviewed 3,613 angioplasty cases retrospectively from 2011 to 2013 and identified 335 patients with SVD treated with device diameter of ≤2.5 mm. DCB-only angioplasty was performed in 172 patients, whereas 163 patients were treated with second-generation DES.DCB patients had smaller reference vessel diameter (2.22 ± 0.30 vs. 2.44 ± 0.19 mm, P 0.001) and received smaller devices (median diameter 2.25 vs. 2.50 mm, P 0.001) compared to the DES group. DES-treated vessels had larger acute lumen gain (1.71 ± 0.48 mm) than DCB (1.00 ± 0.53 mm, P 0.001). Half the patients had diabetes mellitus. While there were more patients presenting with acute coronary syndrome (ACS) in the DCB group (77.9% vs. 62.2%, P = 0.013), they received shorter DAPT (7.4 ± 4.7 vs. 11.8 ± 1.4 months, P 0.001) than the DES group. The 1-year composite major adverse cardiac event rate was 11.6% in the DCB arm and 11.7% in the DES arm (P = 1.000), with target lesion revascularization rate of 5.2% and 3.7%, respectively, (P = 0.601).In this high-risk cohort of patients, DCB-only angioplasty delivered good clinical outcome at 1 year. The results were comparable with DES-treated patients, but had the added benefit of a shorter DAPT regime.

Published
2016

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