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Objective: To evaluate the effect of phacoemulsification with intraocular lens (IOL) implantation on intraocular inflammation using laser flare photometer in eyes with uveitis. Materials and Methods: Sixty-six eyes of 55 consecutive patients followed-up at Istanbul University, Istanbul School of Medicine, Department of Ophthalmology, Uveitis Service undergoing phacoemulsification with posterior chamber intraocular lens implantation between December 2009 and April 2013 were included in this retrospective study. Clinical records of patients were analyzed for demographic data, pre-operative and post-operative best-corrected visual acuity (BCVA), intraocular pressure, and quantitative measurement of inflammation with laser flare photometry. Baseline evaluations were performed 1 day before surgery and follow-up examinations took place at 1, 7, 30, and 90 days after surgery. Main outcome measures were BCVA and quantitative measurement of intraocular inflammation with laser flare photometry. Results: Best-corrected visual acuity improved in 60 eyes and visual loss did not occur in any eye. Median intraocular flare value the day before surgery was 8.2 (range: 3.1-82.2) photons/ms. Postoperatively, median flare value initially increased to 16.8 (range: 0-158) photons/ms on day 1 which was a statistically significant increase compared to preoperative values. Thereafter decreased to 10.40 (range: 0-110) photons/ms on day 7, 11.25 (range: 4.4-145) photons/ms on day 30, and 8.1 (range: 0-84.6) photons/ms on day 90. There was no statistically significant difference between preoperative values and day 90. Conclusion: In uveitic eyes with well-controlled ocular inflammation before surgery, phacoemulsification with IOL implantation appears safe and effective as assessed by changes in the BCVA and laser flare photometry, an objective method to measure intraocular inflammation. [ABSTRACT FROM AUTHOR]

Objective: Ocular tuberculosis is still considered to be a controversial issue in terms of both terminology and diagnostic criteria and treatment options. There is no common diagnostic/treatment algorithm even though new approaches exist.In this study, the results of the treatment of “presumed ocular tuberculosis patients” are evaluated. Materials and Methods: Anti-tuberculosis treatment was given to cases who had latent tuberculosis infection, had no other diagnosis and who did not respond to steroid treatment. These cases were considered to have presumed ocular tuberculosis. Results: Sixty four cases who were considered to have “presumed ocular tuberculosis” received anti-tuberculosis treatment for a minimum of three months and were followed up regularly. The 64 cases were made up of 32 women and 32 men, with a mean age of 42.1±12.09 years. Mean antituberculosis treatment duration was 8.18±2.17 months (3-15 month). After the treatment, 47 (73.4%) of 64 patients reported improvement in vision. Only 36 of these 64 cases (31 bilateral, 5 unilateral, 67 eyes in total) were evaluated with objective vision test before and after the treatment. Disease involvement was uveitis (anterior, intermediate, posterior, panuveitis) in 61 eyes (91%), and retinal vasculitis in 6 eyes (9%). According to the vision analysis among 67 eyes, 42 (62.7%), visual acuities were detected to be improved at variable levels. Mean right eye visual acuity was 0.56±0.049 before treatment, and 0.71±0.047 after treatment (p<0.001). Mean left eye visual acuity was 0.60±0.51 before treatment, and 0.73±0.043 after treatment (p<0.004). Conclusion: In the presence of latent tuberculosis infection, successful results can be obtained with antituberculosis treatment for cases diagnosed as presumed ocular tuberculosis. [ABSTRACT FROM AUTHOR]