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Start Over Author "Jordanova, Maja" Journal journal of medical biochemistry
3 results on '"Jordanova, Maja"'

1. Morphofunctional characteristics of pituitary adrenocorticotropes in an animal model of heat stress

Author

Perčinić-Popovska Florina, Ajdžanović Vladimir, Dinevska-Kofkarovska Suzana, Jordanova Maja, Trifunović Svetlana, Šošić-Jurjević Branka, and Milošević Verica

Subjects
heat stress, acth, male rats, Biochemistry, QD415-436
Abstract

As a result of the global warming, the average ambient temperature during summertime has increased in regions with moderate continental climate. The effects of 24 h exposure to heat stress (35±1 °C) on the morphology and function of pituitary adrenocorti cotropes were examined in adult male Wistar rats. Significant changes in the morphofunctional features of adrenocorti cotropes were found after the heat stress, with no differences noted in the cell shape or localization, com pared to controls. The adrenocorti cotropes cell volume, as well as the volume density, were significantly decreased (p

Published
2011

2. Morfofunkcionalne osobine hipofiznih adrenokortikotropa u životinjskom modelu toplotnog stresa

Author

Perčinić-Popovska, Florina, Šošić-Jurjević, Branka, Ajdžanović, Vladimir, Dinevska-Kofkarovska, Suzana, Jordanova, Maja, Trifunović, Svetlana, Milošević, Verica, Perčinić-Popovska, Florina, Šošić-Jurjević, Branka, Ajdžanović, Vladimir, Dinevska-Kofkarovska, Suzana, Jordanova, Maja, Trifunović, Svetlana, and Milošević, Verica

Abstract

As a result of the global warming, the average ambient temperature during summertime has increased in regions with moderate continental climate. The effects of 24 h exposure to heat stress (35±1 °C) on the morphology and function of pituitary adrenocorti cotropes were examined in adult male Wistar rats. Significant changes in the morphofunctional features of adrenocorti cotropes were found after the heat stress, with no differences noted in the cell shape or localization, com pared to controls. The adrenocorti cotropes cell volume, as well as the volume density, were significantly decreased (p<0.05) by 12.3% and 26.7%, respectively, in comparison with controls. The concentration of plasma adrenocorti cotropic hormone and serum corticosterone in the heat stressed group were significantly decreased (p<0.05) by 21.9% and 27.2%, respectively, compared to controls. These findings suggest that 24 h exposure of adult male rats to heat stress has an inhibitory effect on the morphofunctional characteristics of adrenocorticotropes., Usled globalnog otopljavanja u regionima sa umereno kontinentalnom klimom dolazi do povećanja srednje vrednosti temperature vazduha to kom letnjih meseci. U ovoj studiji ispitivani su efekti 24-časovnog izlaganja to plotnom stresu (35±1 °C) na morfologiju i funkciju hipofiznih adrenokortikotropa kod odraslih pacova Wistar soja. Dobijeni rezultati ukazuju na značajne promene u morfofunkcionalnim osobinama adrenokortiko tropa nakon izlaganja toplotnom stresu, bez uočenih razlika u obliku i lokalizaciji ćelija u poređenju sa kontrolama. Volumen adrenokortikotropa kao i njihova volumenska gustina bili su značajno smanjeni (p<0,05) za 12,3% odnosno 26,7%, u poređenju sa kontrolom. Koncentracije adrenokortikotropnog hormona u plazmi i kortikosterona u serumu u eksperimentalnoj grupi bile su značajno smanjene za 21,9% odnosno 27,2%, u poređenju sa kontrolnim vrednostima. Navedeni rezultati pokazuju da 24-časovno izlaganje odraslih mužjaka pacova toplotnom stresu ima inhibirajući efekat na morfofunkcionalne osobine hipofiznih adrenokortikotropa.

Published
2011

3. MORPHOFUNCTIONAL CHARACTERISTICS OF PITUITARY ADRENOCORTICOTROPES IN AN ANIMAL MODEL OF HEAT STRESS.

Author

Florina Perinčić-Popovska, Ajd`anović, Vladimir, Dinevska-Kofkarovska, Suzana, Jordanova, Maja, Trifunović, Svetlana, Branka Sosić-Jurjević, and Milošević, Verica

Subjects
PHYSIOLOGICAL effects of heat, GLOBAL warming, LABORATORY rats, CELL morphology, CORTICOSTERONE
Abstract

Copyright of Journal of Medical Biochemistry is the property of Society of Medical Biochemists of Serbia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2011

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