1. Demonstration of synchrotron x-ray phase contrast imaging computed tomography of infiltrative transitional cell carcinoma of the prostatic urethra in a dog
- Author
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Michael J. Wesolowski, Rajni Chibbar, Elisabeth Snead, James E. Montgomery, Jaswant Singh, Gregg P. Adams, Murray Pettitt, Bailey Wolkowski, Trinita Barboza, and Pritpal S. Malhi
- Subjects
medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Image Perception, Observer Performance, and Technology Assessment ,Phase-contrast imaging ,Histology ,medicine.disease ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,Prostate cancer ,0302 clinical medicine ,medicine.anatomical_structure ,Transitional cell carcinoma ,Prostatic urethra ,Prostate ,030220 oncology & carcinogenesis ,Abdominal ultrasonography ,X-Ray Phase-Contrast Imaging ,medicine ,Radiology, Nuclear Medicine and imaging ,Radiology ,business - Abstract
Prostatic urethral transitional cell carcinoma with prostatic invasion in a dog was imaged with abdominal radiography and abdominal ultrasonography antemortem. Synchrotron in-line x-ray phase contrast imaging computed tomography (XPCI-CT) was performed on the prostate ex vivo at the Canadian Light Source Synchrotron and compared to histology. XPCI-CT imaging provides greater soft tissue contrast than conventional absorption-based x-ray imaging modalities, permitting visualization of regions of inflammatory cell infiltration, differentiation of invasive versus noninvasive tumor regions, and areas of necrosis and mineralization. This represents the first report of XPCI-CT images of an invasive prostatic urothelial neoplasm in a dog. more...
- Published
- 2016
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