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Cutaneous adverse drug reactions (CADRs) are the common adverse reactions ranging from mild self-limiting skin rash to the life-threatening severe cutaneous adverse reactions. Aims: The aim of the study was to describe the demographic characteristics of patients, different clinical patterns, and implicated drugs. Methods: This was a retrospective study by analyzing the database established for all ADRs reported from January 1, 2018, to December 31, 2018, in a tertiary care teaching hospital in Taipei, Taiwan. Results: A total of 126 cases of CADRs were reported in 2018. The mean age of patients was 59.06 ± 21.63 years, with a peaking at 60–79-year-old (31.7%) and followed by 40–59-year-old (25.4%). The male-to-female ratio was 1.03:1. The most common skin reaction pattern was maculopapular eruptions (59.5%), followed by angioedema (11.9%), phlebitis (6.3%), and urticaria (6.3%). Most of the CADRs were reported with antibacterials (66.7%), followed by anti-inflammatory products (11.9%), contrast media (4.8%), and antithrombotic agents (3.2%). Conclusions: We listed the patient characteristics, each pattern of CADRs, and their associated drugs. Such information could help health-care professionals to assess CADRs and evaluate suspected drugs timely and accurately.

Pretibial myxedema (PM) is an unusual extrathyroidal manifestation of Graves' disease (GD), which affects approximately 1%–5% of the patients. In addition, PM usually occurs in the hyperthyroid state of GD, and the high level of thyroid autoantibodies is considered to be the cause of PM. Here, we present a rare case of a patient who developed PM after undergoing I-131 ablation therapy, with normal levels of thyroid autoantibodies. Our report aims to document the features of PM in a male adult with hypothyroidism and to provide a potential mechanism of the onset of PM.

Basal cell carcinoma (BCC) is the most common type of skin cancer. Polypoid BCC is very rare and distinguishes from other types of BCC by being female predominant, locating on nonsun-exposed areas, prevailing in dark-skinned races, and having large average size, but considered nonaggressive. We report a case of BCC presenting as an inconspicuous polyp. A 40-year-old female sustained a slowly growing mass at the left groin for many years. Physical examination revealed a polypoid mass over the right groin without specific symptoms. Surgical removal with simple polypectomy was performed, whereas the pathological features revealed BCC with polyp feature. There has been no recurrence after the surgery. This case highlights the importance of remaining clinically alert to differentiate a benign-looking polyp.