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Start Over Author "Keh-Weei Tzung" Journal journal of medical virology
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1. Detection of low level of human papilloma virus type 16 DNA sequences in cancer cell lines derived from two well-differentiated nasopharyngeal cancers

Author

Chin-Tarng Lin, David Gutsch, Keh-Weei Tzung, and Eng-Shang Huang

Subjects
Herpesvirus 4, Human, Sequence analysis, viruses, Molecular Sequence Data, Biology, Polymerase Chain Reaction, DNA sequencing, Virus, law.invention, chemistry.chemical_compound, law, Virology, otorhinolaryngologic diseases, Carcinoma, medicine, Tumor Cells, Cultured, Humans, DNA Probes, HPV, Antigens, Viral, Papillomaviridae, Polymerase chain reaction, Base Sequence, Hybridization probe, Cell Differentiation, Nasopharyngeal Neoplasms, medicine.disease, stomatognathic diseases, Infectious Diseases, Nasopharyngeal carcinoma, chemistry, DNA, Viral, DNA
Abstract

Human papilloma virus type 16 (HPV16) related sequences were detected in two EBV-negative nasopharyngeal carcinoma (NPC) cell lines derived from two well-differentiated NPC by polymerase chain reaction. E2 and E6 related sequences of HPV16 were demonstrated using two pairs of primers derived from these two regions. DNA sequence analysis of amplified products excluded the possibility of laboratory viral DNA contamination.

Published
1993

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