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Your search keyword '"Jin, Lixia"' showing total 22 results

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22 results on '"Jin, Lixia"'

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1. Design, Synthesis, and Structure–Activity Relationship Optimization of Pyrazolopyrimidine Amide Inhibitors of Phosphoinositide 3-Kinase γ (PI3Kγ)

2. Discovery of Potent and Selective Methylenephosphonic Acid CD73 Inhibitors

3. Discovery of Potent and Selective PI3Kγ Inhibitors

4. Discovery of AB680: A Potent and Selective Inhibitor of CD73

5. Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73

6. A Selective Prostaglandin E2 Receptor Subtype 2 (EP2) Antagonist Increases the Macrophage-Mediated Clearance of Amyloid-Beta Plaques

7. Discovery of AM-7209, a Potent and Selective 4-Amidobenzoic Acid Inhibitor of the MDM2–p53 Interaction

8. Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres

9. Selective and Potent Morpholinone Inhibitors of the MDM2–p53 Protein–Protein Interaction

10. Discovery of AMG 232, a Potent, Selective, and Orally Bioavailable MDM2–p53 Inhibitor in Clinical Development

11. Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction

12. Discovery of Isonicotinamide Derived β-Secretase Inhibitors: In Vivo Reduction of β-Amyloid

13. Macrocyclic Inhibitors of β-Secretase: Functional Activity in an Animal Model.

18. Macrocyclic Inhibitors of -Secretase:  Functional Activity in an Animal Model

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20. Design, Synthesis, and Structure-Activity Relationship Optimization of Pyrazolopyrimidine Amide Inhibitors of Phosphoinositide 3-Kinase γ (PI3Kγ).

21. Discovery of isonicotinamide derived beta-secretase inhibitors: in vivo reduction of beta-amyloid.

22. Macrocyclic inhibitors of beta-secretase: functional activity in an animal model.

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