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Your search keyword '"Geng, Mei-yu"' showing total 5 results
Start Over Author "Geng, Mei-yu" Journal journal of natural products
5 results on '"Geng, Mei-yu"'

4. Sesquiterpenes and Dimeric Sesquiterpenoids from Sarcandra glabra

Author

He, Xiu-Feng, Yin, Sheng, Ji, Yin-Chun, Su, Zu-Shang, Geng, Mei-Yu, and Yue, Jian-Min

Abstract

Two new sesquiterpenes, sarcandralactones A (1) and B (2), and five new dimeric sesquiterpenoids, sarcandrolides A−E (3−7), along with 10 known compounds were isolated from the whole plants of Sarcandra glabra. Their structures were elucidated on the basis of spectroscopic analysis. Some of the new isolates exhibit significant cytotoxicities when tested against a small panel of tumor cell lines.

Published
2010
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5. Trigoxyphins A-G: diterpenes from Trigonostemon xyphophylloides.

Author

Lin BD, Han ML, Ji YC, Chen HD, Yang SP, Zhang S, Geng MY, and Yue JM

Subjects
Diterpenes chemistry, Diterpenes pharmacology, Drug Screening Assays, Antitumor, Drugs, Chinese Herbal chemistry, Drugs, Chinese Herbal pharmacology, HL-60 Cells, Humans, Molecular Structure, Nuclear Magnetic Resonance, Biomolecular, Phenanthrenes chemistry, Phenanthrenes pharmacology, Plant Stems chemistry, Diterpenes isolation & purification, Drugs, Chinese Herbal isolation & purification, Euphorbiaceae chemistry, Phenanthrenes isolation & purification
Abstract

Six new oxygenated daphnane-type diterpenoids, trigoxyphins A-F (1-6), a phenanthrene-type diterpenoid, trigoxyphin G (7), and two known compounds were isolated from twigs of Trigonostemon xyphophylloides. Their structures were established using spectroscopic methods. Compounds 1 and 2 exhibited strong cytotoxic activity against HL60 (IC(50): 0.27 and 0.49 microM) and A549 (IC(50): 7.5 and 4.9 microM) tumor cell lines, respectively.

Published
2010
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