1. Insect Antifeedants from Croton jatrophoides: Structures of Zumketol, Zumsenin, and Zumsenol
- Author
-
Yukihiro Asaka, Ken-ichi Nihei, Yoshihiro Mine, and Isao Kubo
- Subjects
Limonins ,Stereochemistry ,Acyloin condensation ,Pharmaceutical Science ,Fractionation ,Analytical Chemistry ,chemistry.chemical_compound ,Triterpene ,Biosynthesis ,Drug Discovery ,Animals ,Nuclear Magnetic Resonance, Biomolecular ,Pharmacology ,chemistry.chemical_classification ,Plants, Medicinal ,Molecular Structure ,biology ,Organic Chemistry ,Euphorbiaceae ,Feeding Behavior ,biology.organism_classification ,Kenya ,Terpenoid ,Lepidoptera ,Complementary and alternative medicine ,chemistry ,Larva ,Intramolecular force ,Plant Bark ,Molecular Medicine ,Croton ,Methanol - Abstract
Three new A-seco limonoids, zumketol (1), zumsenin (2), and zumsenol (3), were isolated from a methanol extract of Croton jatrophoides by bioassay-guided fractionation, and their structures were determined by NMR analysis. The alpha-ketol 1 may be biosynthesized via the intramolecular acyloin condensation of a dicarboxylate intermediate.
- Published
- 2005
- Full Text
- View/download PDF