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Comprehensive suitability evaluation of spatial development and construction land is the scientific basis and guarantee for optimizing spatial development pattern and improve its quality and efficiency. It is of great significance for the implementation of regional coordinated development strategy. In this paper, according to the principles of urban-rural integration and land-ocean co-ordination, we selected Liaoning province as a case, the only both coastal and border province in Northeast China. The suitability evaluation index system was established from 3 dimensions, including natural environment, economy and society, and marine function. To evaluate and analyze the suitability of spatial development and constructive land in this province, we integrated the application of Delphi method, cask theory, linear weighted summation model and multi- factors space overlay analysis. The results show that there exist obvious characteristics of spatial differentiation in the suitability of spatial development and construction land throughout Liaoning. The most and more suitable construction land represent an obvious central peripheral structure, and concentrate along both the Shenyang-Dalian axis and the Binhai axis; the most unsuitable construction land shows a north- south symmetric distribution by the Binhai axis, while the more unsuitable construction land shows an east-west symmetric distribution by the Shenyang- Dalian axis. The construction land areas of most suitability, more suitability, more unsuitability, and most unsuitability are 15504.39 km2, 22645.34 km2, 66833.96 km2, and 68720.99 km2, respectively, and the proportions of landocean area are 8.93%, 13.04%, 38.48%, and 39.56%, respectively. The suitability of natural environment plays a fundamental and decisive role in the development and construction of regional land; and the characteristics of agglomeration and dispersion are significantly different at different levels and regions. The suitability of economy and society obviously modifies that of natural environment. The introduction of marine functional zone has greatly expanded the regional land in Liaoning province, but the spatial distribution of marine functional suitability is extremely uneven. And due to the nature of marine functional zone, the space which can be directly developed and constructed is limited, while the space for protection is great. The contradiction between spatial development and ecological environment protection will be still severe for a long time. [ABSTRACT FROM AUTHOR]