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Your search keyword '"Tatsumi M"' showing total 5 results
Start Over Author "Tatsumi M" Journal journal of neural transmission
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5. Association study of C825T polymorphism of the G-protein b3 subunit gene with schizophrenia and mood disorders.

Author

Kunugi, H., Kato, T., Fukuda, R., Tatsumi, M., Sakai, T., and Nanko, S.

Subjects
SCHIZOPHRENIA, AFFECTIVE disorders, MENTAL depression, GENETIC polymorphisms, G proteins, CELLULAR signal transduction
Abstract

Summary. Alterations of G proteins have been implicated in major psychiatric illnesses. A C825T polymorphism of a gene encoding the β3 subunit of heterotrimeric G proteins (GNB3) was reported to be associated with several pathological conditions, such as hypertension and depressive disorder. We examined whether this polymorphism is associated with functional psychoses in a Japanese sample of 370 schizophrenics, 164 bipolars, 68 depressive patients, and 198 controls. We obtained no evidence for an association of the polymorphism with any diagnostic group. [ABSTRACT FROM AUTHOR]

Published
2002
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