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Your search keyword '"Leikfoss, Ingvild Sørum"' showing total 3 results
Start Over Author "Leikfoss, Ingvild Sørum" Journal journal of neuroimmunology
3 results on '"Leikfoss, Ingvild Sørum"'

2. Global DNA methylation changes in treated and untreated MS patients measured over time

Author

Brorson, Ina Skaara, Eriksson, Anna Maria, Høgestøl, Einar August, Leikfoss, Ingvild Sørum, Harbo, Hanne-Cathrin Flinstad, Berge, Tone, Vitelli, Valeria, and Bos, Steffan Daniel

Subjects
Adult, CD4-Positive T-Lymphocytes, Immunology, CD8-Positive T-Lymphocytes, DNA Methylation, Middle Aged, Multiple Sclerosis, Relapsing-Remitting, Neurology, Immunology and Allergy, Humans, Female, Neurology (clinical), Transcriptome, Immunosuppressive Agents
Abstract

Multiple sclerosis (MS) is an autoimmune, neurological disease. We investigated genome-wide DNA methylation profiles of CD4+ and CD8+ T cells from MS patients and healthy controls at baseline and a follow-up visit. Patients were all treatment-naïve at baseline, and either on treatment or remained untreated at the follow-up visit. MS patients show more changes in their T cell DNA methylation profiles as compared to healthy controls over time, with the most pronounced differences observed in the untreated MS patients. These findings underline the potential of DNA methylation as biomarkers in MS.

Published
2021

3. Molecular analysis of the CLEC16A autoimmune risk locus

Author

Leikfoss, Ingvild Sørum, primary, Keshari, Pankaj, additional, Bos, Steffan D., additional, Eriksson, Anna M., additional, Bjølgerud, Anja, additional, Sundvold-gjerstad, Vibeke, additional, Abrahamsen, Greger, additional, Spurkland, Anne, additional, Harbo, Hanne F., additional, and Berge, Tone, additional

Published
2014
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