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Your search keyword '"Zecca, Chiara"' showing total 7 results
Start Over Author "Zecca, Chiara" Journal journal of neurology
7 results on '"Zecca, Chiara"'

1. Implications of therapy interruption on monthly migraine days and modified migraine disability assessment in patients treated with erenumab for chronic and episodic migraine: SQUARE study interim results

Author

Gantenbein, Andreas R., Bonvin, Christophe, Kamm, Christian P., Schankin, Christoph J., Zecca, Chiara, Zieglgänsberger, Dominik, Merki-Feld, Gabriele Susanne, Pohl, Heiko, Rudolph, Nicole, Ryvlin, Philippe, Agosti, Reto, Schäfer, Elisabeth, Meyer, Ina, Kulartz-Schank, Monika, and Arzt, Michael E.

Published
2024
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7. Follow-up of a large population of asymptomatic/oligosymptomatic hyperckemic subjects.

Author

D'Adda E, Sciacco M, Fruguglietti ME, Crugnola V, Lucchini V, Martinelli-Boneschi F, Zecca C, Lamperti C, Comi GP, Bresolin N, Moggio M, and Prelle A

Subjects
Adult, Electromyography, Female, Follow-Up Studies, Humans, Male, Middle Aged, Muscle, Skeletal metabolism, Muscle, Skeletal pathology, Neuromuscular Diseases blood, Prognosis, Creatine Kinase blood, Neuromuscular Diseases epidemiology
Abstract

Six years before the present study we performed a retrospective study of 114 subjects presenting with asymptomatic / oligosymptomatic hyperckemia (raised creatine kinase blood levels), a diagnosis being made in 21 of them. We now present the results of a long-term follow-up in 55 of the still undiagnosed 93 individuals. Most of them have remained asymptomatic and did not develop specific neuromuscular disorders. One subject became frankly symptomatic manifesting limb-girdle weakness. A diagnosis of dystrophinopathy carrier and one of possible type I SMA carrier were indirectly made in another two subjects. Almost all subjects still have hyperckemia, though the mean creatine kinase (CK) value is lower than before. CK levels have become normal in 12 subjects. Two died of neoplasia, and six developed non-neuromuscular disorders. We noted no follow-up differences in terms of CK modifications between subjects with pathological EMG and/or muscle biopsy findings and those with normal findings at first examination.

Published
2006
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