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Start Over Author "Stabellini G." Journal journal of oral pathology & medicine
3 results on '"Stabellini G."'

2. Heterogeneity of fibroblasts derived from human free and attached gingiva. Glycosaminoglycan synthesis and effects of phenytoin (PHT) treatment.

Author

Pagliarini, A, Stabellini, G, Carinci, F, Calura, G, Tognon, M, and Evangelisti, R

Subjects
*CELL culture, *COMPARATIVE studies, *CYTOSKELETAL proteins, *FIBROBLASTS, *GLYCOSAMINOGLYCANS, *GINGIVA, *HYALURONIC acid, *RESEARCH methodology, *MEDICAL cooperation, *PERIODONTIUM, *PHENYTOIN, *RESEARCH, *EVALUATION research, *CHONDROITIN, *CHONDROITIN sulfates, *PHARMACODYNAMICS
Abstract

Two fibroblast populations derived from free and attached gingiva (FGF, AGF) have been compared in cell culture. They exhibited the same morphology and similar cytoskeletal staining patterns, but were different in glycosaminoglycan (GAG) synthesis. FGF released larger quantities of GAGs than AGF in the medium. The extracellular accumulation of hyaluronic acid was higher in FGF than in AGF, whilst the reverse pattern was observed intracellularly. In the case of sulphated GAGs the extracellular concentration, compared to HA, was higher in AGF, while the intracellular concentration was higher in FGF. The two cell populations responded differently to phenytoin (PHT) administration. PHT treatment increased the proportion of intracellular sulphated GAGs in AGF and of extracellular sulphated GAGs in FGF. [ABSTRACT FROM AUTHOR]

Published
1995
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3. Heterogeneity of fibroblasts derived from human free and attached gingiva. Glycosaminoglycan synthesis and effects of phenytoin (PHT) treatment.

Author

PagIiarini, A., Stabellini, G., Carinci, F., Calura, G., Tognon, M., and Evangelisti, R.

Subjects
GINGIVA, FIBROBLASTS, GLYCOSAMINOGLYCANS, PHENYTOIN
Abstract

Two fibroblast populations derived from free and attached gingiva (FGF, AGF) have been compared in cell culture. They exhibited the same morphology and similar cytoskeletal staining patterns, but were different in glycosaminoglycan (GAG) synthesis. FGF released larger quantities of GAGs than AGF in the medium. The extracellular accumulation of hyaluronic acid was higher in FGF than in AGF, whilst the reverse pattern was observed intracellularly. In the case of sulphated GAGs the extracellular concentration, compared to HA, was higher in AGF, while the intracellular concentration was higher in FGE The two cell populations responded differently to phenytoin (PHT) administration. PHT treatment increased the proportion of intracellular sulphated GAGs in AGF and of extracellular sulphated GAGs in FGE [ABSTRACT FROM AUTHOR]

Published
1995
Full Text
View/download PDF

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