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Abstract: Six new triorganotin(IV) complexes, {(R3Sn)2[C7H14(COO)2]}n (R = Me: 1), (R3Sn)2[C7H14(COO)2] (R = Bu: 2; Ph: 3), {(R3Sn)2[C11H9NO2(COO)2]} n ·Y (R = Me, Y = CH2Cl2: 4, R = Bu, Y = 0: 5) and (R3Sn)2[C11H9NO2(COO)2] (R = Ph: 6) have been prepared by treatment of 2,4-diethylglutaric acid, phthalyl-glutamic acid and the corresponding R3SnCl (R = Me, Bu, Ph) with sodium ethoxide in methanol. All the complexes were characterized by elemental analysis, FT-IR, NMR (1H, 13C, 119Sn) spectroscopy, and TGA. Except for 3 and 6, all of the complexes were also characterized by X-ray crystallography. The structural analyses reveal that complexes 1 and 4 have 2D network structures in which 2,4-diethylglutaric acid and phthalyl-glutamic acid act as tetradentate ligands coordinated to trimethyltin(IV) ions. Complex 2 has a dinuclear structure, and complex 5 has a 1D zigzag chain structure and forms a 2D supramolecular framework through intermolecular C–H⋯O interactions. [Copyright &y& Elsevier]

Abstract: Eight new organotin (IV) carboxylates, (R3Sn)4(nap)4 (R = Me 1, n-Bu 2), [(R3Sn) (nap)] n (R = Ph 3, PhCH2 4), (R2Sn) (nap)2 (R = n-Bu 5, Ph 6, PhCH2 7) and {[R2Sn(nap)]2O}2 (R = Me 8) (nap = (S)-(+)-6-methoxy-α-methyl-2-naphthaleneaceto anion) have been synthesized. All of the complexes have been characterized by elemental analysis, FT–IR, NMR (1H, 13C and 119Sn) spectra. Among these complexes, complexes 1, 3, 5 and 8 were also characterized by X-ray crystallography diffraction analysis, and the data of X-ray crystallography diffraction indicated that complexes 1, 3 and 5 are new chiral organotin (IV) carboxylates complexes. The structural analyses show that complex 1 has a tetranuclear Sn4O8 macrocycle structure, complex 3 has a 1D spring-like chiral helical chain with a columnar channel, complex 5 possesses a dimer structure, and complex 8 has a supramolecular chainlike ladder structure through weak intermolecular non-covalent O…O interactions. [Copyright &y& Elsevier]

Abstract: A series of triorganotin (IV) complexes with 2,3,4,5-tetrafluorobenzoic acid and mixed-ligands of the types: R3Sn(O2CC6HF4) m ·L (m =1, L=0, R=Ph 1; m =1, L=Ph3PO, R=Ph 4, Me 5), [R3Sn(O2CC6HF4)] m ·L (m =2, L=4,4′-bipy, R=Ph 2, Me 3; m = n, L=0, R=Me 6), and [R3Sn(O2CC6HF4)·(H2O)] m ·L·C2H5OH (m =2, L=Phen, R=Ph 7, Me 8), (4,4′-bipy=4,4′-bipyridyl; Phen=1,10-phenanthroline), have been synthesized by the reaction of triorganotin chloride and 2,3,4,5-tetrafluorobenzoic acid in the presence of mixed-ligands: 4,4′-bipy, triphenylphosphine oxide, or phen. All complexes were characterized by elemental analysis, IR, 1H, 13C, 119Sn NMR spectroscopy analysis. Except for 5 and 8, all the complexes were also characterized by X-ray crystallography. [Copyright &y& Elsevier]

Abstract: Eight new organoantimony(V) complexes with 1-phenyl-1H-tetrazole-5-thiol [L1H] and 2,5-dimercapto-4-phenyl-1,3,4-thiodiazole [L2H] of the type R n SbL5− n (L=L1: n =4, R= n-Bu 1, Ph 2, n =3, R=Me 3, Ph 4; L=L2: n =4, R= n-Bu 5, Ph 6, n =3, R=Me 7, Ph 8) have been synthesized. All the complexes 1–8 have been characterized by elemental, FT-IR, 1H and 13C NMR analyses. Among them complexes 2, 6 and 8 have also been confirmed by X-ray crystallography. The structure analyses show that the antimony atoms in complexes 2 and 6 display a trigonal bipyramid geometry, while it displays a distorted capped trigonal prism in complex 8 with two intramolecular Sb⋯N weak interactions. Furthermore, the supramolecular structure of 2 has been found to consist of one-dimensional linear molecular chain built up by intermolecular C–H⋯N weak hydrogen bonds, while a macrocyclic dimer has been found in complex 6 linked by intermolecular C–H⋯S weak hydrogen bonds with head-to-tail arrangement. Interestingly, one-dimensional helical chain is recognized in complex 8, which is connected by intermolecular C–H⋯S weak hydrogen bonds. [Copyright &y& Elsevier]

Abstract: The triorganotin(IV) derivatives of 2-mercapto-4-quinazolinone (HSqualone) of the type, R3SnL (R=Ph 1, CH3 2, PhCH2 3, p-F-PhCH2 4, o-F-PhCH2 5, n-Bu 6), were obtained by the reaction of the R3SnCl and HSqualone with 1:1 molar ratio in benzene. All complexes 1–6 were characterized by elemental analyses, IR, 1H and 13C NMR spectroscopy and the crystal structures of complexes 1–3 were also confirmed by X–ray crystallography. The structure analyses reveal that the tin atoms of complexes 1–3 are all distorted tetrahedral geometries. Furthermore, the dimeric structures in complexes 1–3 have also been found linked by intermolecular O–H⋯N or N–H⋯O hydrogen bonding interaction. Interestingly, the dimers of complexes 2 and 3 are further linked into one-dimensional chain through intermolecular C–H⋯S and C–H⋯O weak hydrogen bonding interactions, respectively. [Copyright &y& Elsevier]

Abstract: A series of new triorganotin(IV) pyridinedicarboxylates [(C2H5)3NH][(Me3Sn)3(2,6-pdc)2(H2O)2] (1), [(C2H5)3NH][(Ph3Sn)3(2,6-pdc)2(H2O)2] (2), [(C2H5)3NH]{[(PhCH2)3Sn]3(2,6-pdc)2(H2O)2} (3), [Me3Sn(3,5-pdc)] n (4), [Ph3Sn(3,5-pdc)] n (5), [(PhCH2)3Sn(3,5-pdc)] n (6), [(Me3Sn)2(2,5-pdc)] n (7), [(Ph3Sn)2(2,5-pdc)] n (8) and {[(PhCH2)3Sn]2(2,5-pdc)} n (9) were synthesized by the reaction of trimethyltin(IV), triphenyltin(IV) or tribenzyltin(IV) chloride with 2,6(3,5 or 2,5)-H2pdc (pdc=pyridinedicarboxylate) when triethylamine was added. Complexes 1–9 have been characterized by elemental, IR, 1H, 13C and 119Sn NMR analyses. Among them complexes 1, 5 and 7 have also been characterized by X-ray crystallographic diffraction analyses. Complex 1 has a trinuclear structure and forms a 2D supramolecular structure due to the coordinated water molecules via hydrogen bonds to the pendant O atoms of the carboxyl groups and the N atoms derived of the pyridine ring. Complex 5 forms a 1D polymeric chain by the intermolecular Sn⋯N (N atom derived of pyridine ring) interactions. Complex 7 has a network structure where 2,5-pyridinedicarboxylate acts as a tetradentate ligand coordinated to trimethyltin(IV) ions. [Copyright &y& Elsevier]

Abstract: A series of organotin (IV) complexes with 6-amino-1,3,5-triazine-2,4-dithiol of the type [(R n SnCl4−n )2 (C3H2N4S2)] (n =3: R=Me 1, n-Bu 2, PhCH2 3, Ph 4; n =2: R=Me 5, n-Bu 6, PhCH2 7, Ph 8) have been synthesized. All the complexes 1–8 have been characterized by elemental analysis, IR, 1H and 13C NMR spectra. Among them complexes 1, 4, 5 and 8 have also been characterized by X-ray crystallography diffraction analyses, which revealed that the tin atoms of complexes 1, 4, 5 and 8 are all five-coordinated with distorted trigonal bipyramid geometries. [Copyright &y& Elsevier]

Abstract: The organotin(IV) complexes R2Sn(tpu)2·L [L=2MeOH, R=Me (1); L=0: R=n-Bu (2), Ph (3), PhCH2 (4)], R3Sn(Hthpu) [R=Me (5), n-Bu (6), Ph (7), PhCH2 (8)] and (R2SnCl)2 (dtpu)·L [L=H2O, R=Me (9); L=0: R=n-Bu (10), Ph (11), PhCH2 (12)] have been synthesized, where tpu, Hthpu and dtpu are the anions of 6-thiopurine (Htpu), 2-thio-6-hydroxypurine (H2thpu) and 2,6-dithiopurine (H2dtpu), respectively. All the complexes 1–12 have been characterized by elemental, IR, 1H, 13C and 119Sn NMR spectra analyses. And complexes 1, 2, 7 and 9 have also been determined by X-ray crystallography, complexes 1 and 2 are both six-coordinated with R2Sn coordinated to the thiol/thione S and heterocyclic N atoms but the coordination modes differed. As for complex 7 and 9, the geometries of Sn atoms are distorted trigonal bipyramidal. Moreover, the packing of complexes 1, 2, 7 and 9 are stabilized by the hydrogen bonding and weak interactions. [Copyright &y& Elsevier]

The 18-membered stereoregular diphenyltin macrocycles: {Ph2Sn[S(C6H3NO)O]}3 (8), {Ph2Sn[S(C6H3NO)O]}3·2.67H2O (9) and {Ph2Sn[S(C6H3NO)O]}3·4C6H6 (10) have been synthesized by the reaction of diphenyltin dichloride with 2-mercaptonicotinic acid. The three complexes were characterized by elemental, IR, 1H-NMR analyses. The X-ray crystallography analyses of 9 and 10 were also given. Single crystal X-ray diffraction data reveal that both 9 and 10 are highly symmetrical tri-nuclear cyclic complexes with the ligand 2-mercaptonicotinic acid bridging the adjacent tin atoms. The tin environment is distorted cis-trigonal bipyramid. Weak interaction Sn⋯O was recognized between tin and exocyclic-oxygen atoms. The potential tridentate of endocyclic sulfur atoms make them interesting ligands. [Copyright &y& Elsevier]

Abstract: A series of organotin(IV) complexes with O,O-diethyl phosphoric acid (L1H) and O,O-diisopropyl phosphoric acid (L2H) of the types: [R3Sn·L] n (L=L1, R=Ph 1, R=PhCH2 2, R=Me 3, R=Bu 4; L=L2, R=Ph 9, R=PhCH2 10, R=Me 11, R=Bu 12), [R2Cl Sn·L] n (L=L1, R=Me 5, R=Ph 6, R=PhCH2 7, R=Bu 8; L=L2, R=Me 13, R=Ph 14, R=PhCH2 15, R=Bu 16), have been synthesized. All complexes were characterized by elemental analysis, TGA, IR and NMR (1H, 13C, 31P and 119Sn) spectroscopy analysis. Among them, complexes 1, 2, 3, 5, 8, 9 and 11 have been characterized by X-ray crystallography diffraction analysis. In the crystalline state, the complexes adopt infinite 1D infinite chain structures which are generated by the bidentate bridging phosphonate ligands and the five-coordinated tin centers. [Copyright &y& Elsevier]

Four new organotin complexes, [Me 3 SnO 2 SeC 6 H 4 -F-p] n ( 1 ), [Ph 3 SnO 2 SeC 6 H 4 -F-p] ( 2 ), [Me 2 Sn(O 2 SeC 6 H 4 -F-p) 2 ] n ( 3 ), and [(PhSn) 4 (μ 2 -O) 2 (O 2 SeC 6 H 4 -F-p) 8 ] ( 4 ) have been synthesized via reactions of 4-fluorobenzeneseleninato ligand and the corresponding R 3 SnCl or R 2 SnCl 2 (R = Me, Ph) with sodium ethoxide in methanol. All the complexes have been characterized by X-ray crystallography, elemental analysis, FT-IR, and NMR ( 1 H, 13 C, 119 Sn) spectroscopy. The structural analysis indicates that complex 1 adopts a 1D infinite zigzag chain structure, complex 2 displays a 1D infinite linear polymeric chain structure, complex 3 is 1D helical double-chain polymer containing eight-membered Sn 2 O 4 Se 2 inorganic ring, and complex 4 shows a tetranuclear cage structure containing two Sn–O–Sn motifs connected by bridging [p-F-C 6 H 4 SeO 2 ] - ligands. [ABSTRACT FROM AUTHOR]

Abstract: A mixed tri- and dimethyltin coordination polymer, {[(Me3Sn)(μ2-OH)][Me2Sn(μ3-SCH2CO2)]} (1), has been solvothermally synthesized and structurally characterized by elemental analysis, FT-IR, NMR (1H, 13C, 119Sn) spectra and X-ray crystallography. This complex displays a 1D helical chain structure, in which it can be considered as the tri- and dimethyltin moieties are linked together by the alternate μ2-OH groups and [μ3-SCH2CO2]2− units along the direction. Furthermore, these helical chains are linked together through inter-helix O–H⋯S H-bonding interactions to form a 2D corrugated sheet. [Copyright &y& Elsevier]

• Diorganotin complexes show 2D network containing tetraorganodistannoxane units. • Organotin(IV) carboxylates with n -butyl and phenyl show higher antitumor activity. • Complexes 2 - 3 show lower cytotoxicity than organotin precursors in HBL-100 cells. • Complex 3 can lead to depolarization of mitochondrial membrane potential. • Complex 3 could induce cellular reactive oxygen species accumulation. Seven organotin(IV) complexes, [(R 3 Sn) 2 L] n (R = Me 1 , R = n -Bu 2), [(Ph 3 Sn) 2 L] (3), [(R 2 Sn) 2 L(μ 3 -O)] n (R = Me 4 , R = n -Bu 5), [R 2 SnL(1,10-phen)] n (R = Me 6), [(R 2 SnCl) 2 L(1,10-phen) 2 ] (R = n -Bu 7) derived from 1,4-naphthalenedicarboxylic acid (H 2 L) have been synthesized and characterized by elemental analysis, FT-IR, PXRD, NMR and X-ray crystallography. The single crystal diffraction reveals that complexes 1 and 2 represent 2D network structures, which both contain tetranuclear 26-membered macrocycles. Complexes 3 and 7 display dinuclear tin monomers, which can form 1D infinite chain by C-H ··· O and C-H ··· π interactions. Meanwhile, complexes 4 and 5 display 2D network containing tetraorganodistannoxane unit, while complex 6 adopts a 1D infinite chain structure, which further constructs 2D supramolecular architecture through C-H ··· O intermolecular interactions. What's more, in vitro cytostatic activity of the complexes 1 - 3 against cervical carcinoma cell lines (HeLa), hepatocellular carcinoma cell lines (HepG-2) and human normal breast cell lines (HBL-100) have been investigated, and the results show that organotin derivatives with n -butyl and phenyl group (2 and 3) exhibit significantly higher anticancer activity than complex 1 with methyl group. Meanwhile, organotin(IV) complexes (1 - 3) display lower cytotoxicity than corresponding organotin(IV) precursors [trimethyltin chloride, bis(tri- n -butyltin) oxide and triphenyltin chloride] in HBL-100 cells. Furthermore, cytostatic assessments of complex 3 against HepG-2 cells reveal that the effect of cytostatic and apoptotic may through ROS-mediated pathway. Image, graphical abstract [ABSTRACT FROM AUTHOR]