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Objective To evaluate the efficacy of Q-Switched Nd:YAG laser 1,064nm for the treatment of melasma. Methods A total of 100 patients were included in this study. Treatment area was cleansed and QSwitched Nd:YAG laser 1,064nm, was delivered with settings of 3mm spot size, energy fluence ranging from 500-700 joules and repeated frequency at 6 Hz. Clinical response was assessed by MASI score. Results A total of 100 patients were included in the study. Mean age of the patients was 31.18±5.51 years. There were 13 males (13%) and 87 females (87%). Mean duration of disease was 1.99±0.88 years. Type of melasma was as follows: epidermal 47 (47%), dermal 31 (31%) and mixed 22 (22%). Q-Switched Nd:YAG laser 1,064nm for the treatment of melasma was effective in 59 patients (59%). Conclusion 1064nm Nd:YAG laser was safe, effective and well-tolerated by all patients. [ABSTRACT FROM AUTHOR]

Objective To evaluate the efficacy of 1064nm Q-switched Nd:YAG laser in the treatment of Nevus of Ota. Methods This study was conducted in Department of Dermatology, Unit-II, KEMU/Mayo Hospital, Lahore. A total of 100 patients of nevus of Ota (both unilateral and bilateral) with Fitzpatrick skin type III to V were included in this study. Baseline photographs and Pigment area and Severity Index (PSI) score was recorded. All patients were treated with 1064nm Q-switched Nd:YAG laser at fluence of 500-600 V and frequency of 5Hz. A total of 10 sessions at 2 weeks interval were given. Final assessment was done at 4 weeks after last session. Improvement was measured in terms of percentage reduction in baseline PSI score. Results Mean age of the patients was 24.35±5.70 years. There were 15.0% males and 85.0% females. Majority of the patients had duration of lesion > 15 years. Most of the patients presented with skin type IV. 52.0% patients showed more than 50% clinical improvement. Improvement was higher in females (56%) and in patients with skin type III (50%) and IV (60%). Stratification with regards to age and duration of lesion showed no statistically significant difference. Conclusion Fifty two % of patients of nevus of Ota treated with 1064 nm Q-switched Nd:YAG laser showed more than 50% improvement. [ABSTRACT FROM AUTHOR]