1. Congenital syphilis: unique clinical presentation in three preterm newborns
- Author
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Carlo Dani, Lisa Serafini, Marco Pezzati, Firmino F. Rubaltelli, Luca Filippi, Michele Tronchin, and Giovanna Bertini
- Subjects
Male ,Sexually transmitted disease ,Pediatrics ,medicine.medical_specialty ,Gestational Age ,Cholestasis, Intrahepatic ,Cerebral hemorrhage ,Brain Ischemia ,Lesion ,Fatal Outcome ,Preterm ,Humans ,Medicine ,Neonatology ,Ultrasonography ,Pregnancy ,Cholestasis ,business.industry ,Syphilis, Congenital ,Infant, Newborn ,Obstetrics and Gynecology ,Gestational age ,Endarteritis ,Congenital syphilis ,Newborn ,medicine.disease ,Magnetic Resonance Imaging ,Surgery ,Pediatrics, Perinatology and Child Health ,Syphilis ,medicine.symptom ,business ,Infant, Premature - Abstract
Three preterm newborns affected by congenital syphilis, born to mothers not adequately treated during pregnancy, are described. The clinical picture is characterized by a severe cholestatic hepatopathy and, in the two surviving patients, by an unusually wide ischemic-hemorrhagic lesion of the cerebral parenchyma. This lesion is probably due to a syphilitic endarteritis, and has rarely been described before in preterm infants.
- Published
- 2004
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