Search

Your search keyword '"Basile, Umberto"' showing total 14 results
Start Over Author "Basile, Umberto" Journal journal of personalized medicine
14 results on '"Basile, Umberto"'

1. Kidney Biopsy and Immuno-Rheumatological Diseases: A Retrospective and Observational Study

Author

Gigante, Antonietta, primary, Cianci, Rosario, additional, Villa, Annalisa, additional, Pellicano, Chiara, additional, Giannakakis, Konstantinos, additional, Rosato, Edoardo, additional, Spinelli, Francesca Romana, additional, Basile, Umberto, additional, Racco, Cosimo, additional, Di Virgilio, Elena Maria, additional, Cerbelli, Bruna, additional, and Conti, Fabrizio, additional

Published
2024
Full Text
View/download PDF

3. Laboratory and Clinical Settings of Heavy/Light Chain (HLC) Assays in the Management of Monoclonal Gammopathies and Multiple Myeloma

Author

Napodano, Cecilia, primary, Ioannilli, Laura, additional, Basile, Valerio, additional, Gulli, Francesca, additional, Carnazzo, Valeria, additional, Pignalosa, Stefano, additional, Di Biase, Luigi, additional, Cavaleri, Erica, additional, Racco, Cosimo, additional, Equitani, Francesco, additional, Marino, Mariapaola, additional, and Basile, Umberto, additional

Published
2023
Full Text
View/download PDF

4. Serum Immunoglobulin G (IgG) Subclasses in a Cohort of Systemic Sclerosis Patients

Author

Pellicano, Chiara, primary, Colalillo, Amalia, additional, Cusano, Giuseppina, additional, Palladino, Andrea, additional, Pellegrini, Marica, additional, Callà, Cinzia Anna Maria, additional, Mazzuccato, Giorgia, additional, Carnazzo, Valeria, additional, Pignalosa, Stefano, additional, Di Biase, Luigi, additional, Marino, Mariapaola, additional, Basile, Umberto, additional, and Rosato, Edoardo, additional

Published
2023
Full Text
View/download PDF

5. In Systemic Sclerosis Patients, Peripheral Blood CD21 low B Cells and Serum IL-4 and IL-21 Influence Joint Involvement.

Author

Pellicano, Chiara, Colalillo, Amalia, Carnazzo, Valeria, Redi, Serena, Basile, Valerio, Marino, Mariapaola, Basile, Umberto, and Rosato, Edoardo

Subjects
B cells, SYSTEMIC scleroderma, LOGISTIC regression analysis
Abstract

Systemic sclerosis (SSc) patients have an increased frequency of CD21low B cells and of serum interleukin-4 (IL-4) and IL-21, each possible markers of joint involvement in inflammatory arthritis. The aim of this study was to investigate the possible influence of CD21low B cells, IL-4, and IL-21 on joint involvement in a cohort of 52 SSc patients. The DAS28-ESR was correlated with CD21low B cells (r = 0.452, p < 0.001), IL-4 (r = 0.478, p < 0.001), and IL-21 (r = 0.415, p < 0.001). SSc patients with a DAS28-ESR > 3.2 had more CD21low B cells (12.65% (IQR: 7.11–13.79) vs. 5.08% (IQR: 3.76–7.45), p < 0.01), higher IL-4 levels (132.98 pg/mL (IQR: 99.12–164.12) vs. 100.80 pg/mL (IQR: 62.78–121.13), p < 0.05), and higher IL-21 levels (200.77 pg/mL (IQR: 130.13–302.41) vs. 98.83 pg/mL (IQR: 35.70–231.55), p < 0.01) than patients with a DAS28-ESR ≤ 3.2. The logistic regression analysis models showed that the DAI (OR: 2.158 (95% CI: 1.120; 4.156), p < 0.05) and CD21low B cells (OR: 1.301 (95% CI: 1.099; 1.540), p < 0.01), the DAI (OR: 2.060 (95% CI: 1.082; 3.919), p < 0.05) and IL-4 level (OR: 1.026 (95% CI: 1.006; 1.045), p < 0.01), and the DAI (OR: 1.743 (95% CI: 1.022; 2.975), p < 0.05) and IL-21 level (OR: 1.006 (95% CI: 1.000; 1.011), p < 0.05) were independently associated with a DAS28-ESR > 3.2. An elevated CD21low B cell percentage, IL-4 level, and IL-21 level was associated with higher articular disease activity in patients, suggesting a possible role in the pathogenesis of SSc joint involvement. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

6. Cytokines and Hepatocellular Carcinoma: Biomarkers of a Deadly Embrace

Author

Pocino, Krizia, primary, Stefanile, Annunziata, additional, Basile, Valerio, additional, Napodano, Cecilia, additional, D’Ambrosio, Francesca, additional, Di Santo, Riccardo, additional, Callà, Cinzia Anna Maria, additional, Gulli, Francesca, additional, Saporito, Raffaele, additional, Ciasca, Gabriele, additional, Equitani, Francesco, additional, Basile, Umberto, additional, and Marino, Mariapaola, additional

Published
2022
Full Text
View/download PDF

7. Circulating and Salivary NGF and BDNF Levels in SARS-CoV-2 Infection: Potential Predictor Biomarkers of COVID-19 Disease—Preliminary Data

Author

Biamonte, Filippo, primary, Re, Agnese, additional, Balzamino, Bijorn Omar, additional, Ciasca, Gabriele, additional, Santucci, Daniela, additional, Napodano, Cecilia, additional, Nocca, Giuseppina, additional, Fiorita, Antonella, additional, Marino, Mariapaola, additional, Basile, Umberto, additional, Micera, Alessandra, additional, and Callà, Cinzia Anna Maria, additional

Published
2022
Full Text
View/download PDF

11. Inflammation and Oxidative Stress in Seminal Plasma: Search for Biomarkers in Diagnostic Approach to Male Infertility

Author

Bruno, Carmine, primary, Basile, Umberto, additional, Vergani, Edoardo, additional, Napodano, Cecilia, additional, Oliva, Alessandro, additional, Gulli, Francesca, additional, Meucci, Elisabetta, additional, Silvestrini, Andrea, additional, Orlando, Patrick, additional, Silvestri, Sonia, additional, Tiano, Luca, additional, and Mancini, Antonio, additional

Published
2022
Full Text
View/download PDF

13. Cytokines and Hepatocellular Carcinoma: Biomarkers of a Deadly Embrace.

Author

Pocino, Krizia, Stefanile, Annunziata, Basile, Valerio, Napodano, Cecilia, D'Ambrosio, Francesca, Di Santo, Riccardo, Callà, Cinzia Anna Maria, Gulli, Francesca, Saporito, Raffaele, Ciasca, Gabriele, Equitani, Francesco, Basile, Umberto, and Marino, Mariapaola

Subjects
HEPATOCELLULAR carcinoma, SOMATIC mutation, CYTOKINES, GROWTH factors, ANGIOPOIETINS
Abstract

Hepatocellular carcinoma (HCC) represents a worldwide health matter with a major care burden, high prevalence, and poor prognosis. Its pathogenesis mainly varies depending on the underlying etiological factors, although it develops from liver cirrhosis in the majority of cases. This review summarizes the role of the most interesting soluble factors as biomarkers for early diagnosis and as recommended targets for treatment in accordance with the new challenges in precision medicine. In the premalignant environment, inflammatory cells release a wide range of cytokines, chemokines, growth factors, prostaglandins, and proangiogenic factors, making the liver environment more suitable for hepatocyte tumor progression that starts from acquired genetic mutations. A complex interaction of pro-inflammatory (IL-6, TNF-α) and anti-inflammatory cytokines (TGF-α and -β), pro-angiogenic molecules (including the Angiopoietins, HGF, PECAM-1, HIF-1α, VEGF), different transcription factors (NF-kB, STAT-3), and their signaling pathways are involved in the development of HCC. Since cytokines are expressed and released during the different stages of HCC progression, their measurement, by different available methods, can provide in-depth information on the identification and management of HCC. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

14. Salivary Biomarkers in COVID-19 Patients: Towards a Wide-Scale Test for Monitoring Disease Activity

Author

Napodano, Cecilia, primary, Callà, Cinzia, additional, Fiorita, Antonella, additional, Marino, Mariapaola, additional, Taddei, Eleonora, additional, Di Cesare, Tiziana, additional, Passali, Giulio Cesare, additional, Di Santo, Riccardo, additional, Stefanile, Annunziata, additional, Fantoni, Massimo, additional, Urbani, Andrea, additional, Paludetti, Gaetano, additional, Rapaccini, Gian Ludovico, additional, Ciasca, Gabriele, additional, and Basile, Umberto, additional

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results