1. Effects of sulfur fumigation and heating desulfurization on quality of medicinal herbs evaluated by metabolomics and glycomics: Codonopsis Radix, a pilot study.
- Author
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Xu, Fei, Kong, Ming, Xu, Jin-Di, Xu, Jun, Jiang, Yan, and Li, Song-Lin
- Subjects
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HERBAL medicine , *DESULFURIZATION , *FUMIGATION , *SULFUR , *PILOT projects - Abstract
• Effects of sulfur fumigation and heating desulfurization on CR's quality were studied. • Untargeted/targeted metabolomics and targeted glycomics were integrated to address the effects. • The two processes changed CR's non-saccharide small-molecule metabolome and glycome. • The two processes significantly affected the quality of CR in different ways. • Researches on heating desulfurization and saccharides should be more conducted. Sulfur fumigation and heating desulfurization are used together in the post-harvest processing of many medicinal herbs. However, little is known about the effects of sulfur fumigation on saccharide components, nor about the effects of heating desulfurization on all herbal constituents. In this study, metabolomics and glycomics were integrated to investigate the effects of these two processes on the chemistry of Codonopsis Radix (CR) as a pilot study. The results showed that both sulfur fumigation and heating desulfurization significantly changed the non-saccharide small-molecule metabolome and the glycome of CR in different ways. Chemical mechanisms, such as esterification, glycosidic hydrolysis, esterolysis, amide bond hydrolysis, oxidation and dehydration, are proposed to be involved. These facts strongly inspire that, in addition to investigations of how sulfur fumigation impacts non-saccharide small-molecule metabolites, researches on heating desulfurization and saccharides should be conducted so as to enable accurate, comprehensive evaluation of the quality of sulfur-fumigated herbs. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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