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Your search keyword '"Vaidya RA"' showing total 4 results
Start Over Author "Vaidya RA" Journal journal of postgraduate medicine
4 results on '"Vaidya RA"'

1. Conceptual and methodologic challenges of assessing the short-term efficacy of Guggulu in obesity: data emergent from a naturalistic clinical trial.

Author

Bhatt AD, Dalal DG, Shah SJ, Joshi BA, Gajjar MN, Vaidya RA, Vaidya AB, and Antarkar DS

Subjects
Adult, Female, Humans, Male, Medicine, Ayurvedic, Middle Aged, Pilot Projects, Statistics, Nonparametric, Treatment Outcome, Obesity drug therapy, Plant Extracts therapeutic use, Plants, Medicinal
Abstract

An open comparative trial was conducted in 58 adult obese patients (Body Mass Index > or = 25 kg/square metre). Group I (n = 27), non-drug, was advised diet (1200-1600 cals) and a brisk walk for 30 minutes. Group II, in addition, received Guggulu (Medohar) 1.5-3 gms/day for 30 days. Mean difference in weight loss between Guggulu and non-drug group was 0.32 kg (ns) on day 15 and 0.58 kg on day 30 (ns). The mean weight reduction in patients (> 90 kgs) was 1.92 kg (ns) and 2.25 kg (ns) higher in Guggulu group. All patients weighing > 90 kg lost weight in Guggulu group whilst 3 in non-drug group did not lose weight. Guggulu was tolerated well. The data from this pilot study suggest a synergistic diet-Guggulu interaction over 30 days in patients weighing > 90 kgs which needs to be confirmed in a large placebo controlled study.

Published
1995

4. Initial human trials with an investigational new drug (phase I and 2): planning an management.

Author

Vaidya AB and Vaidya RA

Subjects
Adult, Animals, Chemical Phenomena, Chemistry, Child, Data Collection, Decision Making, Dogs, Dose-Response Relationship, Drug, Drug-Related Side Effects and Adverse Reactions, Female, Humans, In Vitro Techniques, Kinetics, Male, Problem Solving, Clinical Trials as Topic instrumentation, Clinical Trials as Topic methods, Clinical Trials as Topic standards, Human Experimentation, Pharmaceutical Preparations administration & dosage, Pharmaceutical Preparations metabolism, Pharmacology, Pharmacology, Clinical, Research Design standards
Published
1981

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