1. Diabetes, prediabetes, and suicide deaths in a Japanese working population.
- Author
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Fukunaga, Ami, Hu, Huan, Inoue, Yosuke, Nakagawa, Tohru, Honda, Toru, Yamamoto, Shuichiro, Miyamoto, Toshiaki, Okazaki, Hiroko, Shimizu, Makiko, Eguchi, Masafumi, Kochi, Takeshi, Yamamoto, Makoto, Ogasawara, Takayuki, Sasaki, Naoko, Uehara, Akihiko, Imai, Teppei, Nishihara, Akiko, Hori, Ai, Nagahama, Satsue, and Tomita, Kentaro
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PREDIABETIC state , *GLYCOSYLATED hemoglobin , *BLOOD sugar , *SUICIDE , *DIABETES - Abstract
Objective: To examine the association of diabetes and prediabetes with suicide deaths in a Japanese working population.Methods: A nested case-control study was conducted using data from the Japan Epidemiology Collaboration on Occupational Health Study. During 8 years of follow-up, we identified 56 registered cases of suicide death that had information on fasting plasma glucose or glycated hemoglobin A1c at any health check-up during the past 3 years prior to suicide. For each case, we randomly selected five controls matched for age, sex, and worksite. We used the latest health check-up data for analysis. We defined diabetes status based on the American Diabetes Association criteria and used a conditional logistic regression model to investigate the association.Results: Adjusted odds ratios and 95% confidence intervals for suicide death were 0.67 (0.32-1.41) and 3.53 (1.05-11.91) for prediabetes and diabetes, respectively, compared to normoglycemia. Similar results were obtained when diabetes status was exclusively defined by the fasting plasma glucose or glycated hemoglobin A1c level.Conclusion: Diabetes, but not prediabetes, was associated with a higher risk of suicide death, compared with normoglycemia, among a Japanese working population. [ABSTRACT FROM AUTHOR]- Published
- 2020
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