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Trimix/Bimix (combination of papaverine, phentolamine and prostaglandin) have been used for intracavernosal injections (ICI) for many decades as a treatment for erectile dysfunction (ED). Intraurethral Bimix Gel (BMG) provides a stable, therapy with an easy, needle-free, non-refrigerated application, and an attractive alternative for the treatment of ED. This needle-free option for Bimix is an important addition in sexual medicine, as patients require alternatives for ED care. [Extracted from the article]

Intracavernosal Trimix/Bimix injections (ICI) and Intraurethral Bimix Gel (BMG) have been used for many years for the treatment of erectile dysfunction (ED). A combination of PDE5-I with a low dose, needle-free, intraurethral gel may be more attractive than a difficult to stabilize, refrigeration required, needle to the penis for the treatment of ED. [Extracted from the article]

Introduction: There have been many advances in the inflatable penile prosthesis (IPP) since the 1970s. While these devices were initially fraught with mechanical malfunction, the most recent models prove to be much more reliable. Although reservoir complications are not common, when they do occur, it typically involves damage to the surrounding tissues. The ability to recognize and treat these complications is paramount for any surgeon that routinely places IPPs., Aim: The aim of this article was to present a unique reservoir-related complication as well as perform a literature review of reservoir-related complications and techniques for reservoir placement, and provide a summary of dimensions and technical aspects of commonly used reservoirs., Methods: We reviewed a unique reservoir-related complication that presented to our institution with urinary retention and constipation. We also reviewed reservoir-related complications since 1984, reviewed the most recent surgical techniques involved in reservoir placement, and summarized the dimensions and technical characteristics of both the American Medical System and Coloplast reservoirs., Main Outcome Measure: A reservoir-related complication that resulted in urinary retention and constipation is the main outcome measure., Results: Although uncommon, reservoir complications do occur. The most common case report complication in the published literature is bladder erosion followed by external iliac compression, ileal conduit erosion, and small bowel obstruction. The case that presented at our institution was the result of a reservoir that was improperly placed in the perineum, causing urinary retention and constipation due to the compression of the bulbar urethra and rectum., Conclusions: In this era, mechanical failures of IPP reservoirs are rare as most complications occur due to damage of the surrounding tissues. Prevention, diagnosis, and treatment of these complications are important for any surgeon that implants IPPs., (© 2014 International Society for Sexual Medicine.)