1. Large plantar wart caused by human papillomavirus-66 and resolution by topical cidofovir therapy.
- Author
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Davis MD, Gostout BS, McGovern RM, Persing DH, Schut RL, and Pittelkow MR
- Subjects
- AIDS-Related Opportunistic Infections drug therapy, AIDS-Related Opportunistic Infections pathology, Administration, Topical, Adult, Biopsy, Cidofovir, Cytosine administration & dosage, DNA, Viral genetics, Diagnosis, Differential, Female, Foot Dermatoses drug therapy, Foot Dermatoses pathology, Humans, Male, Papillomavirus Infections drug therapy, Papillomavirus Infections pathology, Polymerase Chain Reaction, Skin pathology, Skin virology, Warts drug therapy, Warts pathology, AIDS-Related Opportunistic Infections virology, Antiviral Agents administration & dosage, Cytosine analogs & derivatives, Foot Dermatoses virology, Organophosphonates, Organophosphorus Compounds administration & dosage, Papillomaviridae drug effects, Papillomaviridae genetics, Papillomavirus Infections virology, Warts virology
- Abstract
Warts can be difficult to diagnose and to treat in the setting of human immunodeficiency virus (HIV) infection. A 37-year-old woman with a background of HIV presented with a large verrucous plaque involving her right foot. Human papillomavirus (HPV)-66 was identified in the lesional skin biopsy sample and in scrapings obtained from her cervix. The wart rapidly responded to topical cidofovir therapy. HPV-66 is a novel HPV type to be associated with verruca vulgaris. Topical cidofovir should be further investigated as an alternative treatment modality for verruca vulgaris.
- Published
- 2000
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