Search

Your search keyword '"Andrews, Mark L."' showing total 19 results
Start Over Author "Andrews, Mark L." Journal journal of the american college of cardiology
19 results on '"Andrews, Mark L."'

1. Risk for Life-Threatening Cardiac Events in Patients With Genotype-Confirmed Long-QT Syndrome and Normal-Range Corrected QT Intervals

Author

Goldenberg, Ilan, primary, Horr, Samuel, additional, Moss, Arthur J., additional, Lopes, Coeli M., additional, Barsheshet, Alon, additional, McNitt, Scott, additional, Zareba, Wojciech, additional, Andrews, Mark L., additional, Robinson, Jennifer L., additional, Locati, Emanuela H., additional, Ackerman, Michael J., additional, Benhorin, Jesaia, additional, Kaufman, Elizabeth S., additional, Napolitano, Carlo, additional, Platonov, Pyotr G., additional, Priori, Silvia G., additional, Qi, Ming, additional, Schwartz, Peter J., additional, Shimizu, Wataru, additional, Towbin, Jeffrey A., additional, Vincent, G. Michael, additional, Wilde, Arthur A.M., additional, and Zhang, Li, additional

Published
2011
Full Text
View/download PDF

2. Genotype-Phenotype Aspects of Type 2 Long QT Syndrome

Author

Shimizu, Wataru, primary, Moss, Arthur J., additional, Wilde, Arthur A.M., additional, Towbin, Jeffrey A., additional, Ackerman, Michael J., additional, January, Craig T., additional, Tester, David J., additional, Zareba, Wojciech, additional, Robinson, Jennifer L., additional, Qi, Ming, additional, Vincent, G. Michael, additional, Kaufman, Elizabeth S., additional, Hofman, Nynke, additional, Noda, Takashi, additional, Kamakura, Shiro, additional, Miyamoto, Yoshihiro, additional, Shah, Samit, additional, Amin, Vinit, additional, Goldenberg, Ilan, additional, Andrews, Mark L., additional, and McNitt, Scott, additional

Published
2009
Full Text
View/download PDF

3. Inappropriate Implantable Cardioverter-Defibrillator Shocks in MADIT II

Author

Daubert, James P., primary, Zareba, Wojciech, additional, Cannom, David S., additional, McNitt, Scott, additional, Rosero, Spencer Z., additional, Wang, Paul, additional, Schuger, Claudio, additional, Steinberg, Jonathan S., additional, Higgins, Steven L., additional, Wilber, David J., additional, Klein, Helmut, additional, Andrews, Mark L., additional, Hall, W. Jackson, additional, and Moss, Arthur J., additional

Published
2008
Full Text
View/download PDF

6. Long QT Syndrome and Pregnancy

Author

Seth, Rahul, primary, Moss, Arthur J., additional, McNitt, Scott, additional, Zareba, Wojciech, additional, Andrews, Mark L., additional, Qi, Ming, additional, Robinson, Jennifer L., additional, Goldenberg, Ilan, additional, Ackerman, Michael J., additional, Benhorin, Jesaia, additional, Kaufman, Elizabeth S., additional, Locati, Emanuela H., additional, Napolitano, Carlo, additional, Priori, Silvia G., additional, Schwartz, Peter J., additional, Towbin, Jeffrey A., additional, Vincent, G. Michael, additional, and Zhang, Li, additional

Published
2007
Full Text
View/download PDF

7. Corrected QT Variability in Serial Electrocardiograms in Long QT Syndrome

Author

Goldenberg, Ilan, primary, Mathew, Jehu, additional, Moss, Arthur J., additional, McNitt, Scott, additional, Peterson, Derick R., additional, Zareba, Wojciech, additional, Benhorin, Jesaia, additional, Zhang, Li, additional, Vincent, G. Michael, additional, Andrews, Mark L., additional, Robinson, Jennifer L., additional, and Morray, Brian, additional

Published
2006
Full Text
View/download PDF

8. The Cost Effectiveness of Implantable Cardioverter-Defibrillators

Author

Zwanziger, Jack, primary, Hall, W. Jackson, additional, Dick, Andrew W., additional, Zhao, Hongwei, additional, Mushlin, Alvin I., additional, Hahn, Rebecca Marron, additional, Wang, Hongkun, additional, Andrews, Mark L., additional, Mooney, Cathleen, additional, Wang, Hongyue, additional, and Moss, Arthur J., additional

Published
2006
Full Text
View/download PDF

10. Reduction in Ventricular Tachyarrhythmias With Statins in the Multicenter Automatic Defibrillator Implantation Trial (MADIT)-II

Author

Vyas, Anant K., primary, Guo, Hongsheng, additional, Moss, Arthur J., additional, Olshansky, Brian, additional, McNitt, Scott A., additional, Hall, W. Jackson, additional, Zareba, Wojciech, additional, Steinberg, Jonathan S., additional, Fischer, Avi, additional, Ruskin, Jeremy, additional, and Andrews, Mark L., additional

Published
2006
Full Text
View/download PDF

11. Predictive Value of Ventricular Arrhythmia Inducibility for Subsequent Ventricular Tachycardia or Ventricular Fibrillation in Multicenter Automatic Defibrillator Implantation Trial (MADIT) II Patients

Author

Daubert, James P., primary, Zareba, Wojciech, additional, Hall, W. Jackson, additional, Schuger, Claudio, additional, Corsello, Andrew, additional, Leon, Angel R., additional, Andrews, Mark L., additional, McNitt, Scott, additional, Huang, David T., additional, and Moss, Arthur J., additional

Published
2006
Full Text
View/download PDF

14. Modulating effects of age and gender on the clinical course of long QT syndrome by genotype

Author

Zareba, Wojciech, primary, Moss, Arthur J, additional, Locati, Emanuela H, additional, Lehmann, Michael H, additional, Peterson, Derick R, additional, Hall, W.Jackson, additional, Schwartz, Peter J, additional, Vincent, G.Michael, additional, Priori, Silvia G, additional, Benhorin, Jesaia, additional, Towbin, Jeffrey A, additional, Robinson, Jennifer L, additional, Andrews, Mark L, additional, Napolitano, Carlo, additional, Timothy, Katherine, additional, Zhang, Li, additional, and Medina, Aharon, additional

Published
2003
Full Text
View/download PDF

17. Corrected QT Variability in Serial Electrocardiograms in Long QT Syndrome The Importance of the Maximum Corrected QT for Risk Stratification

Author

Goldenberg, Ilan, Mathew, Jehu, Moss, Arthur J., McNitt, Scott, Peterson, Derick R., Zareba, Wojciech, Benhorin, Jesaia, Zhang, Li, Vincent, G. Michael, Andrews, Mark L., Robinson, Jennifer L., and Morray, Brian

Subjects
congenital, hereditary, and neonatal diseases and abnormalities, cardiovascular system, cardiovascular diseases, circulatory and respiratory physiology
Abstract

ObjectivesWe evaluated the incremental prognostic information provided by multiple corrected QT (QTc) measurements on serial electrocardiograms (ECGs) in patients with the inherited long QT syndrome (LQTS).BackgroundA baseline QTc of ≥500 ms has been shown to be associated with increased risk of cardiac events among LQTS patients. However, the value of QTc measurements on follow-up ECGs in risk assessment has not been determined.MethodsThe risk of a first LQTS-related cardiac event during adolescence was assessed in 375 patients enrolled in the International LQTS Registry for whom serial follow-up ECGs were recorded before age 10.ResultsThe mean ± SD difference between the minimum and maximum QTc values on serial ECGs recorded in study patients was 47 ± 40 ms. The maximum QTc interval recorded before age 10 was the strongest predictor of cardiac events during adolescence (adjusted hazard ratio [HR] = 2.74; p < 0.001). Other follow-up QTc measures, including the baseline, the mean, and the most recent QTc interval recorded before age 10, were less significant risk factors. After adjusting for the maximum QTc value during follow-up, no significant association remained between the baseline QTc value and the risk of subsequent cardiac events (HR = 1.04; p = 0.91).ConclusionsIn LQTS patients, there is a considerable variability in QTc measures in serial follow-up ECGs. The maximum QTc interval provides incremental prognostic information beyond the baseline measurement. We suggest that risk stratification in LQTS patients should include follow-up ECG data.

Full Text
View/download PDF

18. The Cost Effectiveness of Implantable Cardioverter-Defibrillators Results From the Multicenter Automatic Defibrillator Implantation Trial (MADIT)-II

Author

Zwanziger, Jack, Hall, W. Jackson, Dick, Andrew W., Zhao, Hongwei, Mushlin, Alvin I., Hahn, Rebecca Marron, Wang, Hongkun, Andrews, Mark L., Mooney, Cathleen, Wang, Hongyue, and Moss, Arthur J.

Subjects
health care economics and organizations
Abstract

ObjectivesWe sought to evaluate the cost implications of the implantable cardioverter-defibrillator (ICD), using utilization, cost, and survival data from the Multicenter Automatic Defibrillator Implantation Trial (MADIT)-II.BackgroundThis trial showed that prophylactic implantation of a defibrillator reduces the rate of mortality in patients who experienced a previous myocardial infarction and low left ventricular ejection fraction. Given the size of the eligible population, the cost effectiveness of the ICD has substantial implications.MethodsOur research comprises the cost-effectiveness component of the randomized controlled trial, MADIT-II, based on utilization, cost, and survival information from 1,095 U.S. patients who were assigned randomly to receive an ICD or conventional medical care. Utilization data were converted to costs using a variety of national and hospital-specific data. The incremental cost-effectiveness ratio (iCER) was calculated as the difference in discounted costs divided by the difference in discounted life expectancy within 3.5 years. Secondary analyses included projections of survival (using three alternative assumptions), corresponding cost assumptions, and the resulting cost-effectiveness ratios until 12 years after randomization.ResultsDuring the 3.5-year period of the study, the average survival gain for the defibrillator arm was 0.167 years (2 months), the additional costs were $39,200, and the iCER was $235,000 per year-of-life saved. In three alternative projections to 12 years, this ratio ranged from $78,600 to $114,000.ConclusionsThe estimated cost per life-year saved by the ICD in the MADIT-II study is relatively high at 3.5 years but is projected to be substantially lower over the course of longer time horizons.

Full Text
View/download PDF

19. Inappropriate Implantable Cardioverter-Defibrillator Shocks in MADIT II Frequency, Mechanisms, Predictors, and Survival Impact

Author

Daubert, James P., Zareba, Wojciech, Cannom, David S., McNitt, Scott, Rosero, Spencer Z., Wang, Paul, Schuger, Claudio, Steinberg, Jonathan S., Higgins, Steven L., Wilber, David J., Klein, Helmut, Andrews, Mark L., Hall, W. Jackson, and Moss, Arthur J.

Abstract

ObjectivesThis study sought to identify the incidence and outcome related to inappropriate implantable cardioverter-defibrillator (ICD) shocks, that is, those for nonventricular arrhythmias.BackgroundThe MADIT (Multicenter Automatic Defibrillator Implantation Trial) II showed that prophylactic ICD implantation improves survival in post-myocardial infarction patients with reduced ejection fraction. Inappropriate ICD shocks are common adverse consequences that may impair quality of life.MethodsStored ICD electrograms from all shock episodes were adjudicated centrally. An inappropriate shock episode was defined as an episode during which 1 or more inappropriate shocks occurred; another inappropriate ICD episode occurring within 5 min was not counted. Programmed parameters for patients with and without inappropriate shocks were compared.ResultsOne or more inappropriate shocks occurred in 83 (11.5%) of the 719 MADIT II ICD patients. Inappropriate shock episodes constituted 184 of the 590 total shock episodes (31.2%). Smoking, prior atrial fibrillation, diastolic hypertension, and antecedent appropriate shock predicted inappropriate shock occurrence. Atrial fibrillation was the most common trigger for inappropriate shock (44%), followed by supraventricular tachycardia (36%), and then abnormal sensing (20%). The stability detection algorithm was programmed less frequently in patients receiving inappropriate shocks (17% vs. 36%, p = 0.030), whereas other programming parameters did not differ significantly from those without inappropriate shocks. Importantly, patients with inappropriate shocks had a greater likelihood of all-cause mortality in follow-up (hazard ratio 2.29, p = 0.025).ConclusionsInappropriate ICD shocks occurred commonly in the MADIT II study, and were associated with increased risk of all-cause mortality.

Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results