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2. 2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy: Executive Summary

Author

Anita Deswal, Michelle M. Kittleson, Matthew W. Martinez, Christopher Semsarian, Lauren L. Evanovich, Michael A. Burke, Judy Hung, Steve R. Ommen, Christina Y. Miyake, Paul F. Kantor, Paul Sorajja, Carey Kimmelstiel, Seema Mital, Jose A. Joglar, Sharlene M. Day, Perry M. Elliott, Hartzell V. Schaff, Mark S. Link, and Martin S. Maron

Subjects
medicine.medical_specialty, Executive summary, business.industry, medicine.medical_treatment, Psychological intervention, Hypertrophic cardiomyopathy, Guideline, 030204 cardiovascular system & hematology, Implantable cardioverter-defibrillator, medicine.disease, 03 medical and health sciences, 0302 clinical medicine, Documentation, Health care, medicine, 030212 general & internal medicine, Dosing, Cardiology and Cardiovascular Medicine, Intensive care medicine, business
Abstract

Aim This executive summary of the hypertrophic cardiomyopathy clinical practice guideline provides recommendations and algorithms for clinicians to diagnose and manage hypertrophic cardiomyopathy in adult and pediatric patients as well as supporting documentation to encourage their use. Methods A comprehensive literature search was conducted from January 1, 2010, to April 30, 2020, encompassing studies, reviews, and other evidence conducted on human subjects that were published in English from PubMed, EMBASE, the Cochrane Collaboration, Agency for Healthcare Research and Quality reports, and other relevant databases. Structure Many recommendations from the earlier hypertrophic cardiomyopathy guidelines have been updated with new evidence or a better understanding of earlier evidence. This summary operationalizes the recommendations from the full guideline and presents a combination of diagnostic work-up, genetic and family screening, risk stratification approaches, lifestyle modifications, surgical and catheter interventions, and medications that constitute components of guideline directed medical therapy. For both guideline-directed medical therapy and other recommended drug treatment regimens, the reader is advised to follow dosing, contraindications and drug-drug interactions based on product insert materials.

Published
2020
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3. 2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy

Author

Steve R. Ommen, Seema Mital, Michael A. Burke, Sharlene M. Day, Anita Deswal, Perry Elliott, Lauren L. Evanovich, Judy Hung, José A. Joglar, Paul Kantor, Carey Kimmelstiel, Michelle Kittleson, Mark S. Link, Martin S. Maron, Matthew W. Martinez, Christina Y. Miyake, Hartzell V. Schaff, Christopher Semsarian, and Paul Sorajja

Subjects
Cardiology and Cardiovascular Medicine
Published
2020
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5. TCT-34 Reduction of Infarct Size in Anterior ST-Segment Elevation Myocardial Infarction (STEMI) With LAD Occlusion and LV Unloading Using a Micro-axial Pump for 30 Minutes Before PCI: Per-Protocol Analysis of the STEMI Door to Unload (DTU) Pilot Study

Author

Navin Kapur, Jeffrey Moses, Haroon Faraz, Zachary George, Vijay Iyer, Richard Karas, Carey Kimmelstiel, Gerald Koenig, Ryan Madder, Perwaiz Meraj, Raymond Kim, Theodore Schreiber, David Wohns, James Udelson, Gregg Stone, and William O’Neill

Subjects
Cardiology and Cardiovascular Medicine
Published
2022
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7. Cangrelor With and Without Glycoprotein IIb/IIIa Inhibitors in Patients Undergoing Percutaneous Coronary Intervention

Author

Muthiah Vaduganathan, Robert A. Harrington, Gregg W. Stone, Efthymios N. Deliargyris, Ph. Gabriel Steg, C. Michael Gibson, Christian W. Hamm, Matthew J. Price, Alberto Menozzi, Jayne Prats, Steven Elkin, Kenneth W. Mahaffey, Harvey D. White, Deepak L. Bhatt, Fernando Cura, Miguel Ballarino, Anibal Agustín Damonte, Diego Grinfeld, Carlos Alejandro Álvarez, Alberto Fernandez, Ahmad Farshid, Brendan Gunalingam, Craig Jeurgens, Harry Lowe, Hisham Hallani, Greg Nelson, Gishel New, Ronald Dick, Jeffrey Lefkovits, Stephen Duffy, Nick Bett, Raibhan Yadav, Paul Garrahy, Ron Lehman, Philip Aylward, John Horowitz, Matthew Worthley, David Cross, Jaime Rankin, Peter Thompson, Phil Roberts-Thomson, Rohan Jayasinghe, Con Aroney, Kurt Huber, Franz Leisch, Johann Altenberger, Georg Gaul, Thomas Neunteufl, Franz Weidinger, Herwig Schuchlenz, Heinrich Weber, Werner Benzer, Paulo Rossi, Breno Almeida, Antonio Godinho, Fabio Vilas-Boas, Luciano Vacanti, Renato Serpa, José Antonio Jatene, Gilmar Reis, Jamil Saad, Marcos Marino, Roberto Botelho, Constantino Costantini, Ricardo Wang, Dalton Precoma, Miguel Rati, Luis Bodanese, Euler Manenti, João Paulo Zouvi, Rogerio Tumelero, Arthur Herdy, Eulogio Martinez Filho, Antônio Carvalho, Roberto Franken, Lawrence Title, Charles Lazzam, Francois Reeves, Tamaz Shaburishvili, Gulnara Chapidze, Merab Mamatsashvili, Irakli Khintibidze, Hubertus Heuer, Hans-Georg Olbrich, Sabine Genth-Zotz, Sven Moebius-Winkler, Michael Buerke, Stefan Hoffmann, Peter Radke, Helge Moellmann, Hugo Katus, Hans-Friedrich Voehringer, Christian Hengstenberg, Volker Klauss, Johannes Brachmann, Aftab Khan, Sampath Kumar, Padinhare Mohanan, Praveen Chandra, Maddury Rao, S.S. Ramesh, Keyur Parikh, Arun Srinivas, Nakul Sinha, V.S. Prakash, Shirish Hiremath, Anil Mishra, Sanjeeb Roy, Kamal Sethi, Ashwani Mehta, Tejas Patel, Suman Bhandari, Milind Gadkari, Stefano De Servi, Giuseppe Musumeci, Bernardo Cortese, Giancarlo Marenzi, Raffaele De Caterina, Ralph Stewart, Gerard Devlin, Scott Harding, John Elliott, Gerard Wilkins, Douglas Scott, Slawomir Dobrzycki, Waldemar Dorniak, Dariusz Dudek, Zbigniew Gasior, Jaroslaw Hiczkiewicz, Zdzislawa Kornacewicz-Jach, Leszek Kubik, Krzysztof Kuc, Jerzy Kuzniar, Walentyna Mazurek, Jakub Ostrowski, Michal Tendera, Andrzej Wisniewski, Elzbieta Zinka, Krzysztof Zmudka, Jana Pawła, Maciej Kosmider, null Seweryna, Andres Iñiguez, Rafael Melgares, Francisco Goicolea, Jose Hernandez, Javier Zueco, Igor Kraiz, Mykola Vatutin, Anatoliy Polyakov, Yury Sokolov, Kenneth House, Charles Campbell, Timothy Trageser, Kenneth Baran, Neal Kleiman, Roberto Medina, Roger Hill, M. Zubair Jafar, David Drenning, Herbert Ladley, Ahed Nahhas, Alan Niederman, Amit Goyal, William Abernethy, Naseem Jaffrani, Richard Zelman, Brian Negus, Jose Marquez, Ehtisham Mahmud, William French, John Paulowski, Charles Pollack, Mark Mines, Robert Federici, Marc Schweiger, Kalim Habet, Ofsman Quintana, Thomas Nygaard, Steve Orlow, Douglas Spriggs, Ivan Chavez, Mark Warner, Richard Paulus, David Cochran, Cary Hirsch, Ajay Virmani, Peter Soukas, Nalin Srivastava, L. Norman Ferrier, Annapoorna Kini, Mark Greenberg, Howard Herrmann, Valerian Fernandes, Barry Bertolet, Ron Waksman, Joseph Henderson, Harinder Gogia, Maged Amine, Kourosh Mastali, Thomas Stuckey, Peter Hui, Luigi Pacifico, Todd Caulfield, Wilson Ginete, William Ballard, Robert Iwaoka, Joseph Stella, Vijay Misra, Costa Andreou, Michele Voeltz, Wayne Batchelor, Cezar Staniloae, Sanford Gips, Jeffrey Kramer, Paul Mahoney, John Wang, Prospero Gogo, David Rizik, Rex Winters, Garry MacKenzie, Stephen Jenkins, Paul Teirstein, Pierre Leimgruber, J. Christopher Scott, Seth Krauss, Steven Rohrbeck, Robert Martin, Gustavo Grieco, Louis Cannon, Don Westerhausen, F. David Fortuin, Steven Schulman, Joel Cohn, Brent McLaurin, Jorge Saucedo, Robert Wozniak, Jack Hall, Kevin Marzo, Merrill Krolick, Lawrence Gimple, Eric Hockstad, Arsenio Rodriguez, John Kao, Adhir Shroff, Michael Attubato, Ramon Quesada, Ernesto Rivera, Dean Kereiakes, Russell Raymond, Thomas Amidon, David Lee, Spencer King, John Douglas, Abnash Jain, J. Patrick Kleaveland, Mitchell Driesman, Krishna Kumar, Glen Kowalchuk, Behzad Taghizadeh, Lawrence Barr, Keith Benzuly, Tarek Helmy, Duane Pinto, Joseph Aragon, Reginald Low, Phillip Horwitz, Thomas LeGalley, Dominick Angiolillo, Rajesh Sachdeva, Kenneth Kent, Luis Gruberg, Richard Bach, Thomas Pow, Charles O'Shaughnessy, Shing Wong, Saeed R. Shaikh, Arthur Reitman, Mark Lawrence, Alejandro Garcia Escudero, Carlos Poy, Miguel Miceli, Antonio Pocovi, Hugo Londero, Jorge Baccaro, Leonid Polonetsky, Aliaksey Karotkin, Leanid Shubau, Eduardo Maffini, Bruno Machado, José Airton, Valter Lima, Jose Jatene, Marco Perin, Paulo Caramori, Iran Castro, Ivan Manukov, Mladen Grigorov, Plamen Milkov, Julia Jorgova, Svetoslav Georgiev, Nizar Rifai, Alexander Doganov, Ivo Petrov, William Hui, Jean-Francois Tanguay, Marek Richter, Frantisek Tousek, Zdenek Klimsa, Michal Padour, Jan Mrozek, Marian Branny, Zdenek Coufal, Stanislav Simek, Vladimir Rozsival, Leos Pleva, Josef Stasek, Petr Kala, Ladislav Groch, Viktor Kocka, Rajesh Jain, Darshan Banker, Lanka Krishna, Hasit Joshi, Jaspal Arneja, Virgilijus Grinius, Sigute Norkiene, Birute Petrauskiene, Rolf Michels, Melvin Tjon, Hans de Swart, Robbert de Winter, Harvey White, Malcolm Abernethey, Alexander Osiev, Kirill Linev, Svetlana Kalinina, Svetlana Baum, Elena Kosmachova, Zaur Shogenov, Valentin Markov, Svetlana Boldueva, Olga Barbarash, Victor Kostenko, Elena Vasilieva, Aleksey Gruzdev, Victor Lusov, Pavel Dovgalevsky, Oleg Azarin, Sergey Chernov, Olga Smolenskaya, Alexey Duda, Viliam Fridrich, Marian Hranai, Martin Studenčan, Peter Kurray, John Bennett, Pieter Blomerus, Laurence Disler, Johannes Engelbrecht, Eric Klug, Robert Routier, Tjaart Venter, Nico Van Der Merwe, Anthony Becker, Kwang-Soo Cha, Seung-Hwan Lee, Sang-Jin Han, Tae Jin Youn, Seung-Ho Hur, Hong Seog Seo, Hun-Sik Park, Chong-Yun Rhim, Wook-Bum Pyun, Hyunmin Choe, Myung-Ho Jeong, Jong-Seon Park, Eak-Kyun Shin, Felipe Hernández, Jaume Figueras, Rosana Hernández, José Ramón López-Minguez, José Ramón González Juanatey, Ramón López Palop, Guillermo Galeote, Noppadol Chamnarnphol, Wacin Buddhari, Nakarin Sansanayudh, Srun Kuanprasert, William Penny, Charles Lui, Garfield Grimmett, Venkatraman Srinivasan, Kevin Ariani, Waqor Khan, James Blankenship, Steven Eisenberg, Jerry Greenberg, Jeffrey Breall, Harish Chandna, Paul Tolerico, Georges Nseir, Adam Greenbaum, Pierre Istfan, Joel Sklar, Robert Smith, Nicholaos Xenopoulos, Mahesh Mulumudi, James Hoback, Gregory Eaton, John Griffin, Ramin Ebrahimi, Robert Lundstrom, Dogan Temizer, Kenneth Tam, Jose Suarez, Amish Raval, Jay Kaufman, Emmanouil Brilakis, Michael Stillabower, Kathleen Quealy, Boris Nunez, Bruce Samuels, Agustin Argenal, Vankeepuram Srinivas, Andrew Rosenthal, Pradyumna Tummala, Paul Myers, Nelson LaMarche, Michael Chan, Daniel Simon, Richard Kettelkamp, Gary Schaer, Edward Kosinski, Maurice Buchbinder, Mukesh Sharma, Mark Goodwin, J. Tift Mann, David Holmes, Sunil Rao, Michael Azrin, Roger Gammon, Kreton Mavromatis, Abdel Ahmed, Marcel Zughaib, R. Jeffrey Westcott, Ash Jain, Georg Delle-Karth, Jamil Abdalla Saad, Alexandre Abizaid, Carlos Augusto Formiga Areas, Expedito E. Ribeiro, Fabio Rossi Dos Santos, Rogerio Tadeu Tumelero, Roberto Vieira Botelho, Borislav Atzev, Boicho Boichev, Georgi Grigorov, Nikolay Penkov, Boris Zehirov, Pavel Cervinka, Petr Hajek, David Horak, Petr Kmonicek, Jan Sitar, Nodar Emukhvari, George Khabeishvili, Steffen Behrens, Harald Darius, Martin Dissmann, Stephan Fichtlscherer, Wolfgang Franz, Tobias Geisler, Britta Goldmann, Andreas Mugge, Tudor Poerner, Gert Richardt, Christoph Stellbrink, Nikos Werner, Ezio Bramucci, Gennaro Galasso, Andrea Picchi, Patrizia Presbitero, Alexander Sasse, Szyszka Andrzej, Witold Dubaniewicz, Jaroslaw Kasprzak, Andrzej Kleinrok, Andrzej Rynkiewicz, Cezary Sosnowski, Radoslaw Targonski, Jaroslaw Trebacz, Adam Witkowski, Yakov Dovgalevsky, Ivan Gordeev, Prokhor Pavlov, Sergey Shalaev, Irina Sukmanova, Alexey Yakovlev, Sarana Boonbaichaiyapruck, Pinij Kaewsuwanna, Dilok Piyayotai, Imran Arif, Joseph Cinderella, Brent Davis, Chandanreddy Devireddy, Mark Dorogy, Norman Ferrier, Daniel Fisher, Robert Foster, John Galla, Raghava Gollapudi, James Hermiller, Richard Heuser, Zubair Jafar, Carey Kimmelstiel, Scott Kinlay, James Leggett, Dustin Letts, Michael Lipsitt, Joaquin Martinez-Arraras, Marc Mayhew, Paul McWhirter, Ayoub Mirza, William O'Riordan, John Petersen, Hector Picon, Mark Picone, Matthew Price, Virender Sethi, Craig Siegel, Daniel Steinberg, Jeffrey Tauth, Mladen Vidovich, Jonathan Waltman, and Michael Wilensky

Subjects
Male, medicine.medical_specialty, Ticlopidine, medicine.medical_treatment, Myocardial Ischemia, Hemorrhage, Platelet Glycoprotein GPIIb-IIIa Complex, 030204 cardiovascular system & hematology, Cohort Studies, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cangrelor, P2Y12, Double-Blind Method, Internal medicine, medicine, Humans, Prospective Studies, 030212 general & internal medicine, Angioplasty, Balloon, Coronary, Infusions, Intravenous, Aged, Aspirin, business.industry, Percutaneous coronary intervention, Middle Aged, Clopidogrel, Adenosine Monophosphate, Surgery, Treatment Outcome, chemistry, Glycoprotein IIb/IIIa inhibitors, Conventional PCI, Eptifibatide, Cardiology, Platelet aggregation inhibitor, Drug Therapy, Combination, Female, Cardiology and Cardiovascular Medicine, business, Platelet Aggregation Inhibitors, medicine.drug
Abstract

Background Cangrelor, an intravenous, reversible P2Y12 antagonist, is approved for use in patients undergoing percutaneous coronary intervention (PCI). Objectives This study sought to evaluate the efficacy and safety of cangrelor compared with clopidogrel in subgroups that did and did not receive glycoprotein IIb/IIIa inhibitors (GPIs). Methods This pooled, patient-level analysis of the 3 CHAMPION (Cangrelor versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition) trials analyzed all randomized patients who underwent PCI and received the study drug (n = 24,902). Only bailout/rescue GPI use was permitted, except in CHAMPION PCI, in which routine or bailout/rescue GPI use was at the site investigator’s discretion. The primary efficacy endpoint was the composite of all-cause mortality, myocardial infarction, ischemia-driven revascularization, or stent thrombosis at 48 h after randomization. Results Overall, 3,173 patients (12.7%) received a GPI, most commonly eptifibatide (69.4%). Despite variation in indications for GPIs, baseline characteristics were well balanced between the cangrelor and clopidogrel arms in subsets receiving and not receiving GPIs. Rates of the primary composite endpoint were lower with cangrelor compared with clopidogrel in patients who did (4.9% vs. 6.5%; odds ratio [OR]: 0.74; 95% confidence interval [CI]: 0.55 to 1.01) or did not receive a GPI (3.6% vs. 4.4%; OR: 0.82; 95% CI: 0.72 to 0.94; Pint = 0.55). Cangrelor did not increase the primary safety endpoint, GUSTO-defined severe/life-threatening bleeding, in patients who did (0.4% vs. 0.5%; OR: 0.71; 95% CI: 0.25 to 1.99) or did not receive GPIs (0.2% vs. 0.1%; OR: 1.56; 95% CI: 0.80 to 3.04; Pint = 0.21). GPI use was associated with increased risk of bleeding in both treatment arms. Conclusions Cangrelor’s efficacy in reducing ischemic complications in patients undergoing PCI was maintained irrespective of GPI administration. GPI use was associated with substantially higher bleeding rates, regardless of the randomization to cangrelor or clopidogrel. (A Clinical Trial to Demonstrate the Efficacy of Cangrelor [PCI]: NCT00305162 ; Cangrelor Versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition [PLATFORM]: NCT00385138 ; A Clinical Trial Comparing Cangrelor to Clopidogrel Standard Therapy in Subjects Who Require Percutaneous Coronary Intervention [PCI] [CHAMPION PHOENIX] [CHAMPION]: NCT01156571 )

Published
2017
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8. COMORBIDITY BURDEN AND ADVERSE OUTCOMES AFTER TRANSCATHETER AORTIC VALVE REPLACEMENT

Author

Y. Zhan, Daniel R. Feldman, Benjamin S. Wessler, Andrew Weintraub, Mikhail Romashko, Benjamin Koethe, Sonika Patel, Carey Kimmelstiel, Charles D. Resor, David W. Allen, and Hassan Rastegar

Subjects
medicine.medical_specialty, Transcatheter aortic, Adverse outcomes, business.industry, medicine.medical_treatment, medicine.disease, Comorbidity, Valve replacement, Comorbid disease, medicine, Cardiology and Cardiovascular Medicine, Intensive care medicine, business, After treatment
Abstract

In high-risk patients treated with transcatheter aortic valve replacement (TAVR), half of all deaths after treatment are due to non-cardiac causes. Comorbid disease burden can be a major determinant of outcomes after TAVR. We sought to assess the relationship of comorbid disease burden at the time

Published
2020
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9. IMPROVED PHARMACOLOGIC PROFILE OF A NOVEL, LIQUID ASPIRIN FORMULATION COMPARED WITH ENTERIC COATED ASPIRIN-A POOLED, PATIENT LEVEL ANALYSIS OF TWO RANDOMIZED CROSSOVER STUDIES

Author

Philippe Gabriel Steg, George Dangas, Carey Kimmelstiel, Efthymios N. Deliargyris, Dominick J. Angiolillo, Weihong Fan, Roxana Mehran, Jayne Prats, and Deepak L. Bhatt

Subjects
medicine.medical_specialty, Aspirin, business.industry, Internal medicine, Enteric coated aspirin, Medicine, Cardiology and Cardiovascular Medicine, business, Gastroenterology, medicine.drug
Published
2020
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10. IMPACT OF WEIGHT ON THE ANTIPLATELET EFFECTS OF ASPIRIN-RESULTS OF A POOLED ANALYSIS OF TWO RANDOMIZED CROSSOVER STUDIES COMPARING A LIQUID ASPIRIN FORMULATION WITH ENTERIC COATED ASPIRIN

Author

George Dangas, Philippe Gabriel Steg, Weihong Fan, Carey Kimmelstiel, Dominick J. Angiolillo, Jayne Prats, Deepak L. Bhatt, Roxana Mehran, and Efthymios N. Deliargyris

Subjects
Aspirin, medicine.medical_specialty, Pooled analysis, business.industry, Enteric coated aspirin, Internal medicine, medicine, Cardiology and Cardiovascular Medicine, business, Gastroenterology, medicine.drug
Published
2020
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11. TCT-825 A Novel Post-Closure Method for Hemostatic Removal of the Impella CP Pump Among Patients With Cardiogenic Shock

Author

Sarah Newman, Colin S. Hirst, Andrew Weintraub, Haval Chweich, Navin K. Kapur, and Carey Kimmelstiel

Subjects
medicine.medical_specialty, Percutaneous, business.industry, Cardiogenic shock, Closure (topology), 030204 cardiovascular system & hematology, medicine.disease, Surgery, 03 medical and health sciences, 0302 clinical medicine, Device removal, Hemostasis, Medicine, 030212 general & internal medicine, Cardiology and Cardiovascular Medicine, business, Impella
Abstract

Use of percutaneous mechanical circulatory support (MCS) is growing exponentially. Vascular complications remain a concern, and best practices for device removal do not currently exist. We describe a novel post-closure technique for Impella CP removal and immediate hemostasis. Eight consecutive

Published
2019
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12. TCT-433 Death by Insurance: Insurance payer mix is tied to clinical outcomes in patients with acute myocardial infarction complicated by cardiogenic shock

Author

Gabriel A. Hernandez, David Zisa, Carey Kimmelstiel, Carlos Dávila, Michele Esposito, Mahek Shah, and Navin K. Kapur

Subjects
medicine.medical_specialty, business.industry, Cardiogenic shock, medicine, In patient, Myocardial infarction, Cardiology and Cardiovascular Medicine, Intensive care medicine, medicine.disease, business
Published
2017
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13. TCT-687 Alcohol Ablation and Surgical Myectomy Lead to Excellent Clinical Outcomes When Prescribed According to Consensus Guidelines: A Single Center Experience

Author

Carlos Dávila, Saleh Alshalash, Andrew Weintraub, David Zisa, Benjamin S. Wessler, Navin K. Kapur, Carey Kimmelstiel, Martin S. Maron, Johny S. Kuttab, and Ethan J. Rowin

Subjects
medicine.medical_specialty, business.industry, Medicine, Cardiology and Cardiovascular Medicine, business, Single Center, Lead (electronics), Surgery, Alcohol ablation
Published
2017
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14. TCT-828 Clinical Outcomes Following Focal Ablation – a New Technique for the Performance of Alcohol Septal Ablation

Author

Benjamin S. Wessler, Ethan J. Rowin, Navin K. Kapur, Andrew Weintraub, Catherine Carroll, James E. Udelson, Carlos Dávila, Martin S. Maron, Youssef Rahban, Sophie Wells, David Zisa, and Carey Kimmelstiel

Subjects
Alcohol septal ablation, medicine.medical_specialty, business.industry, Medicine, Focal ablation, Radiology, Cardiology and Cardiovascular Medicine, business
Published
2018
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15. TCT-578 Two-Year 'Real-World' Outcomes Following Implantation of the ION™ Paclitaxel-Eluting Platinum Chromium Coronary Stent in Routine Clinical Practice: Results From the ION U.S. Post-Approval Registry

Author

Thomas K. Pow, Robert C. Stoler, Keith D. Dawkins, Rick Ganim, Robert Kayser, Carey Kimmelstiel, Louis Cannon, Dominic J. Allocco, and R. Lee Jobe

Subjects
chemistry.chemical_compound, medicine.medical_specialty, Paclitaxel, chemistry, business.industry, medicine.medical_treatment, Coronary stent, Real world outcomes, Medicine, Routine clinical practice, business, Cardiology and Cardiovascular Medicine, Surgery
Published
2014
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16. TCT-180 One-Year 'Real-World' Outcomes Following Implantation of the ION(tm) Paclitaxel-Eluting Platinum Chromium Coronary Stent in Routine Clinical Practice: Primary Endpoint Results of the ION U.S. Post-Approval Registry

Author

Louis Cannon, Paul R. Myers, Carey Kimmelstiel, Anthony White, Timothy Grady, Paul Underwood, R J Hill, Keith D. Dawkins, and Mirle A. Kellett

Subjects
medicine.medical_specialty, business.industry, medicine.medical_treatment, Real world outcomes, Surgery, chemistry.chemical_compound, Paclitaxel, chemistry, Coronary stent, medicine, Clinical endpoint, Routine clinical practice, business, Cardiology and Cardiovascular Medicine
Published
2013
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17. TCT-132 Utility of the SAVE Score as a Predictor of Survival in Cardiogenic Shock Requiring VA-ECMO or Impella for Acute Mechanical Circulatory Support

Author

Shiva Annamalai, Ryan O'Kelly, Sudeep Kuchibhotla, Navin K. Kapur, David Zisa, Leslie Lussier, Amanda R. Vest, Adel Ghuloom, Andrew Mullin, Michael S. Kiernan, Tobias Rheude, Carey Kimmelstiel, Catalina Breton, and Michele Esposito

Subjects
medicine.medical_specialty, business.industry, Cardiogenic shock, medicine.medical_treatment, medicine.disease, surgical procedures, operative, Internal medicine, Circulatory system, medicine, Cardiology, Extracorporeal membrane oxygenation, In patient, cardiovascular diseases, Cardiology and Cardiovascular Medicine, business, health care economics and organizations, Impella
Abstract

The Survival After Veno-arterial ECMO (SAVE) score estimates survival in patients receiving veno-arterial extracorporeal membrane oxygenation (VA-ECMO). A lower SAVE score predicts lower survival. We explored the utility of SAVE as a predictor of survival in cardiogenic shock (CS) patients

Published
2016
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18. PROSTHESIS PATIENT MISMATCH IN TRANSCATHETER AORTIC VALVE REPLACEMENT IS RELATED TO BODY SIZE INDEXED ANNULAR DIMENSION

Author

Eleonora Avenatti, Hassan Rastegar, Ayan R. Patel, Natesa G. Pandian, Vilma Castaneda, Duc Thinh Pham, Andrew Weintraub, Valeria Milazzo, and Carey Kimmelstiel

Subjects
medicine.medical_specialty, Transcatheter aortic, business.industry, medicine.medical_treatment, Body size, Prosthesis, Surgery, Dimension (vector space), Valve replacement, Internal medicine, Cardiology, Medicine, Cardiology and Cardiovascular Medicine, business
Published
2016
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19. TCT-500 Prasugrel Is A More Potent Platelet Inhibitor Than Clopidogrel In Bivalirudin-Treated Patients. Comparative Effects of Two Thienopyridines On ADP And Thrombin Receptor Antagonism As Assessed By Aggregometry

Author

Athan Kuliopulos, Ryan Stevenson, Carey Kimmelstiel, Andrew Weintraub, Vilma Castaneda, and Navin K. Kapur

Subjects
Prasugrel, business.industry, Pharmacology, Clopidogrel, Platelet inhibitor, Thienopyridines, Thrombin receptor, medicine, Bivalirudin, cardiovascular diseases, Cardiology and Cardiovascular Medicine, business, Antagonism, circulatory and respiratory physiology, medicine.drug
Published
2014
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20. Flow cytometric analysis of platelet padgem expression during percutaneous transluminal coronary angioplasty

Author

John Golden, Theresa M. Palabrica, Deeb N. Salem, Carey Kimmelstiel, John J. Smith, Mark Aronovitz, David Scott, and Marvin A. Konstam

Subjects
Percutaneous transluminal coronary angioplasty, medicine.medical_specialty, business.industry, Internal medicine, Cardiology, Medicine, Platelet, business, Cardiology and Cardiovascular Medicine
Published
1991
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21. LONGITUDINAL STENT DEFORMATION: QUANTITATIVE CORONARY ANGIOGRAPHIC ANALYSIS FROM THE PERSEUS WH AND PLATINUM WH RANDOMIZED CONTROLLED CLINICAL TRIALS

Author

Ian T. Meredith, Dean J. Kereiakes, Dominic J. Allocco, Stefan Verheye, Keith D. Dawkins, Jeffrey J. Popma, Gregg W. Stone, Louis Cannon, Paul S. Teirstein, Carey Kimmelstiel, and David E. Kandzari

Subjects
medicine.medical_specialty, business.industry, medicine.medical_treatment, Stent, Stent deformation, equipment and supplies, Surgery, Clinical trial, surgical procedures, operative, medicine, Radiology, cardiovascular diseases, Cardiology and Cardiovascular Medicine, business
Abstract

Stent platform characteristics, including material and design, influence both periprocedural and late performance. Recent reports have suggested susceptibility of novel thin-strut coronary stents to incur longitudinal stent deformation during or following deployment. This analysis focuses on the ION

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22. TCT-745 Guideline Based Referral for Septal Reduction Therapy In Patients With Hypertrophic Cardiomyopathy Is Associated With Excellent Clinical Outcomes: Longitudinal Follow-Up Of A Large, Single-Center Experience

Author

Hassan Rastegar, Martin S. Maron, Carey Kimmelstiel, Yuvrajsinh J. Parmar, Saket Sanghai, Johny S. Kuttab, and Ethan J. Rowin

Subjects
medicine.medical_specialty, Referral, business.industry, medicine.medical_treatment, Hypertrophic cardiomyopathy, Guideline, Single Center, medicine.disease, Internal medicine, Emergency medicine, Cardiology, Medicine, In patient, Cardiology and Cardiovascular Medicine, business, Reduction (orthopedic surgery)
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