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Your search keyword '"Karl Stamm"' showing total 4 results
Start Over Author "Karl Stamm" Journal journal of the american college of cardiology
4 results on '"Karl Stamm"'

1. Noninvasive Assay for Donor Fraction of Cell-Free DNA in Pediatric Heart Transplant Recipients

Author

Donna K. Mahnke, Huan Ling Liang, Pippa Simpson, Steven Zangwill, Aoy Tomita-Mitchell, William S. Ragalie, Ronit Katz, Karl Stamm, Steven J. Kindel, and Michael E. Mitchell

Subjects
Graft Rejection, Pathology, medicine.medical_specialty, business.industry, Myocardium, 030204 cardiovascular system & hematology, 030230 surgery, Pediatrics, Endomyocardial biopsy, 03 medical and health sciences, chemistry.chemical_compound, surgical procedures, operative, 0302 clinical medicine, Text mining, Cell-free fetal DNA, chemistry, Population Surveillance, Heart Transplantation, Humans, Medicine, Cardiology and Cardiovascular Medicine, business, Cell-Free Nucleic Acids, DNA
Abstract

There is a compelling clinical need for a noninvasive alternative to endomyocardial biopsy (EMB) for the surveillance of rejection in heart transplant recipients. We and others have reported on donor cell-free deoxyribonucleic acid (cfDNA), which is shed from the donor allograft and is elevated

Published
2018
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2. Highly Sensitive Noninvasive Cardiac Transplant Rejection Monitoring Using Targeted Quantification of Donor-Specific Cell-Free Deoxyribonucleic Acid

Author

Pip M. Hidestrand, Mats Hidestrand, Mary Goetsch, Steven Zangwill, Arnold Oliphant, Pippa Simpson, D. Woodrow Benson, Huan Ling Liang, Michael E. Mitchell, Aoy Tomita-Mitchell, James S. Tweddell, Stuart Berger, Chesney Castleberry, Gail Stendahl, and Karl Stamm

Subjects
Cell specific, Heart transplantation, medicine.medical_specialty, Pathology, Graft failure, business.industry, medicine.medical_treatment, Urology, Gold standard (test), Highly sensitive, Endomyocardial biopsy, Catheter, Medicine, business, Cardiology and Cardiovascular Medicine, Cardiac transplant rejection
Abstract

To the Editor: Approximately 20,000 cardiac transplant recipients currently reside in the United States. Rejection remains a major cause of graft failure and requires lifelong surveillance. The current gold standard for monitoring rejection is catheter-based endomyocardial biopsy (EMB), which is

Published
2014
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3. NOVEL ASSAY TO CALCULATE DONOR FRACTION OF CELL-FREE DNA IN HEART TRANSPLANTATION

Author

Huan Ling Liang, Pippa Simpson, Pip M. Hidestrand, Mats Hidestrand, Steven J. Kindel, Steven Zangwill, Ronit Katz, Michael E. Mitchell, William S. Ragalie, Mary Goetsch, Karl Stamm, Gail Stendahl, Mahnke Donna, and Aoy Tomita-Mitchell

Subjects
Heart transplantation, medicine.medical_specialty, business.industry, medicine.medical_treatment, Urology, Fraction (chemistry), 030204 cardiovascular system & hematology, Turnaround time, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, 030228 respiratory system, Cell-free fetal DNA, chemistry, Medicine, Cardiology and Cardiovascular Medicine, business, Throughput (business), DNA, Blinded study
Abstract

Donor fraction (DF) of cell-free DNA (cf-DNA) has been proposed as a noninvasive surveillance method in heart transplantation. We present our pilot experience with a novel assay to quantify DF (%) with a clinically practical throughput and turnaround time. A blinded study was performed in which

Published
2018
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4. EXOME SEQUENCING REVEALS NOVEL VARIANTS IN TMEM59L AND KLHL26 ASSOCIATED WITH A FAMILIAL CASE OF EBSTEIN'S ANOMALY AND LEFT VENTRICULAR NONCOMPACTION

Author

Michele A. Frommelt, Huan Ling Liang, Michael E. Mitchell, Aoy Tomita-Mitchell, Richard J. Willes, Karl Stamm, Donna K. Mahnke, and Lauren M. North

Subjects
medicine.medical_specialty, Familial case, business.industry, Ebstein's anomaly, Internal medicine, medicine, Cardiology, Left ventricular noncompaction, Cardiology and Cardiovascular Medicine, medicine.disease, business, Exome sequencing
Published
2017
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