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Start Over Author "Rohatgi, Anand" Journal journal of the american college of cardiology
31 results on '"Rohatgi, Anand"'

10. NOVEL BIOMARKERS OF CORONARY ARTERY CALCIUM INCIDENCE OR PROGRESSION: INSIGHTS FROM THE DALLAS HEART STUDY

Author

Eisen, Alon, primary, Kornowski, Ran, additional, Hamdan, Ashraf, additional, Talmor-Barkan, Yeela, additional, Witberg, Guy, additional, Deshpande, Kaivalya, additional, Paixao, Andre, additional, Ayers, Colby, additional, Joshi, Parag, additional, Rohatgi, Anand, additional, Khera, Amit, additional, de Lemos, James, additional, and Neeland, Ian, additional

Published
2019
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16. LONG-TERM ASSOCIATION OF LDL CHOLESTEROL WITH CARDIOVASCULAR MORTALITY IN INDIVIDUALS AT LOW 10-YEAR RISK OF ATHEROSCLEROTIC CARDIOVASCULAR DISEASE: THE COOPER CENTER LONGITUDINAL STUDY

Author

Abdullah, Shuaib, primary, Defina, Laura, additional, Leonard, David, additional, Barlow, Carolyn, additional, Radford, Nina, additional, Rohatgi, Anand, additional, McGuire, Darren, additional, de Lemos, James, additional, Berry, Jarett, additional, and Khera, Amit, additional

Published
2016
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20. Body Fat Distribution and Incident Cardiovascular Disease in Obese Adults

Author

Neeland, Ian J., primary, Turer, Aslan T., additional, Ayers, Colby R., additional, Berry, Jarett D., additional, Rohatgi, Anand, additional, Das, Sandeep R., additional, Khera, Amit, additional, Vega, Gloria L., additional, McGuire, Darren K., additional, Grundy, Scott M., additional, and de Lemos, James A., additional

Published
2015
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29. The Relationship of Body Mass and Fat Distribution With Incident Hypertension Observations From the Dallas Heart Study

Author

Chandra, Alvin, Neeland, Ian J., Berry, Jarett D., Ayers, Colby R., Rohatgi, Anand, Das, Sandeep R., Khera, Amit, McGuire, Darren K., de Lemos, James A., and Turer, Aslan T.

Subjects
obesity, hypertension, visceral fat, body fat distribution
Abstract

BackgroundObesity has been linked to the development of hypertension, but whether total adiposity or site-specific fat accumulation underpins this relationship is unclear.ObjectivesThis study sought to determine the relationship between adipose tissue distribution and incident hypertension.MethodsNormotensive participants enrolled in the Dallas Heart Study were followed for a median of 7 years for the development of hypertension (systolic blood pressure [SBP] ≥140 mm Hg, diastolic blood pressure ≥90 mm Hg, or initiation of blood pressure medications). Visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) was quantified by magnetic resonance imaging and proton-spectroscopic imaging, and lower body fat (LBF) was imaged by dual-energy x-ray absorptiometry. Multivariable relative risk regression was performed to test the association between individual fat depots and incident hypertension, adjusting for age, sex, race/ethnicity, diabetes, smoking, SBP, and body mass index (BMI).ResultsAmong 903 participants (median age, 40 years; 57% women; 60% nonwhite; median BMI 27.5 kg/m2), 230 (25%) developed incident hypertension. In multivariable analyses, higher BMI was significantly associated with incident hypertension (relative risk: 1.24; 95% confidence interval: 1.12 to 1.36, per 1-SD increase). However, when VAT, SAT, and LBF were added to the model, only VAT remained independently associated with incident hypertension (relative risk: 1.22; 95% confidence interval: 1.06 to 1.39, per 1-SD increase).ConclusionsIncreased visceral adiposity, but not total or subcutaneous adiposity, was robustly associated with incident hypertension. Additional studies will be needed to elucidate the mechanisms behind this association.

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30. Lifetime Risks for Cardiovascular Disease Mortality by Cardiorespiratory Fitness Levels Measured at Ages 45, 55, and 65 Years in Men The Cooper Center Longitudinal Study

Author

Berry, Jarett D., Willis, Benjamin, Gupta, Sachin, Barlow, Carolyn E., Lakoski, Susan G., Khera, Amit, Rohatgi, Anand, de Lemos, James A., Haskell, William, and Lloyd-Jones, Donald M.

Subjects
exercise testing, cardiovascular disease, epidemiology, cardiovascular diseases, lifetime risk
Abstract

ObjectivesThe purpose of this study was to determine the association between fitness and lifetime risk for cardiovascular disease (CVD).BackgroundHigher levels of traditional risk factors are associated with marked differences in lifetime risks for CVD. However, data are sparse regarding the association between fitness and the lifetime risk for CVD.MethodsWe followed up 11,049 men who underwent clinical examination at the Cooper Institute in Dallas, Texas, before 1990 until the occurrence of CVD death, non-CVD death, or attainment of age 90 years (281,469 person-years of follow-up, median follow-up 25.3 years, 1,106 CVD deaths). Fitness was measured by the Balke protocol and categorized according to treadmill time into low, moderate, and high fitness, with further stratification by CVD risk factor burden. Lifetime risk for CVD death determined by the National Death Index was estimated for fitness levels measured at ages 45, 55, and 65 years, with non-CVD death as the competing event.ResultsDifferences in fitness levels (low fitness vs. high fitness) were associated with marked differences in the lifetime risks for CVD death at each index age: age 45 years, 13.7% versus 3.4%; age 55 years, 34.2% versus 15.3%; and age 65 years, 35.6% versus 17.1%. These associations were strongest among persons with CVD risk factors.ConclusionsA single measurement of low fitness in mid-life was associated with higher lifetime risk for CVD death, particularly among persons with a high burden of CVD risk factors.

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