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Your search keyword '"Sun, Benjamin"' showing total 17 results
Start Over Author "Sun, Benjamin" Journal journal of the american college of cardiology
17 results on '"Sun, Benjamin"'

6. 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope

Author

Shen, Win-Kuang, primary, Sheldon, Robert S., additional, Benditt, David G., additional, Cohen, Mitchell I., additional, Forman, Daniel E., additional, Goldberger, Zachary D., additional, Grubb, Blair P., additional, Hamdan, Mohamed H., additional, Krahn, Andrew D., additional, Link, Mark S., additional, Olshansky, Brian, additional, Raj, Satish R., additional, Sandhu, Roopinder Kaur, additional, Sorajja, Dan, additional, Sun, Benjamin C., additional, and Yancy, Clyde W., additional

Published
2017
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7. Transcatheter Mitral Valve Replacement for Patients With Symptomatic Mitral Regurgitation

Author

Muller, David W.M., primary, Farivar, Robert Saeid, additional, Jansz, Paul, additional, Bae, Richard, additional, Walters, Darren, additional, Clarke, Andrew, additional, Grayburn, Paul A., additional, Stoler, Robert C., additional, Dahle, Gry, additional, Rein, Kjell A., additional, Shaw, Marty, additional, Scalia, Gregory M., additional, Guerrero, Mayra, additional, Pearson, Paul, additional, Kapadia, Samir, additional, Gillinov, Marc, additional, Pichard, Augusto, additional, Corso, Paul, additional, Popma, Jeffrey, additional, Chuang, Michael, additional, Blanke, Philipp, additional, Leipsic, Jonathon, additional, Sorajja, Paul, additional, Muller, David, additional, Conellan, Mark, additional, Spina, Roberto, additional, Pedersen, Wesley, additional, Farivar, R. Saeid, additional, Sun, Benjamin, additional, Scalia, Gregory, additional, Grayburn, Paul, additional, Stoler, Robert, additional, Hebeler, Robert, additional, Rein, Kjell Arne, additional, Fiane, Arnt, additional, Guerrero, Maya, additional, Feldman, Ted, additional, Salinger, Michael, additional, Smart, Steven, additional, Mick, Stephanie, additional, Krishnaswamy, Amar, additional, Blanke, Philippe, additional, Carroll, John, additional, George, Isaac, additional, Missov, Emil, additional, and Kiser, Andrew, additional

Published
2017
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9. Importance of Angina in Patients With Coronary Disease, Heart Failure, and Left Ventricular Systolic Dysfunction

Author

Jolicœur, E. Marc, primary, Dunning, Allison, additional, Castelvecchio, Serenella, additional, Dabrowski, Rafal, additional, Waclawiw, Myron A., additional, Petrie, Mark C., additional, Stewart, Ralph, additional, Jhund, Pardeep S., additional, Desvigne-Nickens, Patrice, additional, Panza, Julio A., additional, Bonow, Robert O., additional, Sun, Benjamin, additional, San, Tan Ru, additional, Al-Khalidi, Hussein R., additional, Rouleau, Jean L., additional, Velazquez, Eric J., additional, and Cleland, John G.F., additional

Published
2015
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17. Pre-Operative Risk Factors of Bleeding and Stroke During Left Ventricular Assist Device Support An Analysis of More Than 900 HeartMate II Outpatients

Author

Boyle, Andrew J., Jorde, Ulrich P., Sun, Benjamin, Park, Soon J., Milano, Carmelo A., Frazier, O. Howard, Sundareswaran, Kartik S., Farrar, David J., and Russell, Stuart D.

Subjects
LVAD, heart failure, pump thrombosis, bleeding, stroke, HeartMate II
Abstract

ObjectivesThis study sought to determine the pre-operative risk factors related to late bleeding, stroke, and pump thrombosis in patients with HeartMate II (HMII) left ventricular assist devices (LVADs) (Thoratec Corporation, Pleasanton, California) that might influence tailored improvements in patient management.BackgroundAdverse events in LVAD patients remain high. It is unclear whether pre-operative characteristics influence the likelihood of the development of post-operative hemorrhagic or thrombotic complications. Knowing which patients are at greater risk might assist in tailoring anticoagulation therapy for certain patients.MethodsAdvanced heart failure patients (n = 956) discharged from the hospital after LVAD implantation in the HMII bridge to transplantation (n = 405) and destination therapy (n = 551) clinical trials were retrospectively evaluated. Bleeding requiring surgery or transfusion of >2 U of packed red blood cells, stroke (hemorrhagic and ischemic), and pump thrombosis were tracked from hospital discharge until patient outcome.ResultsAdverse event rates for post-discharge bleeding (0.67 events/patient-year) were higher than those for hemorrhagic stroke (0.05), ischemic stroke (0.04), and pump thrombosis (0.03). The main sites of bleeding included gastrointestinal (45% of events), wound (12%), and epistaxis (4%). Older age (>65 years) (hazard ratio [HR]: 1.31), lower pre-operative hematocrit (≤31%) (HR: 1.31), ischemic etiology (HR: 1.35), and female (HR: 1.45) were statistically significant multivariable risk factors for bleeding. Female (HR: 1.92) and 65 years of age and younger (HR: 1.94) were multivariable risk factors for hemorrhagic stroke, whereas female (HR: 1.84) and history of diabetes (HR: 1.99) were risk factors for ischemic stroke. Female (HR: 1.90) and higher body mass index (HR: 1.71/10 kg/m2 increase) were also multivariable risk factors for pump thrombosis.ConclusionsThe risk of bleeding and thrombotic events during LVAD support differs by patient demographics, including sex, age, body mass index, and etiology of heart failure. Further studies should focus on the potential of tailored anticoagulation strategies in these subgroups.

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