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Your search keyword '"Graham G. Walmsley"' showing total 12 results
Start Over Author "Graham G. Walmsley" Journal journal of the american college of surgeons
12 results on '"Graham G. Walmsley"'

1. Engrailed-1 Identifies the Fibroblast Lineage Responsible for the Transition from Fetal Scarless to Adult Scarring Cutaneous Wound Repair

Author

Rahul Sinha, H. Peter Lorenz, Zeshaan N. Maan, Michael S. Hu, Tripp Leavitt, Michael T. Longaker, Graham G. Walmsley, Geoffrey C. Gurtner, Irving L. Weissman, and Clement D. Marshall

Subjects
Pathology, medicine.medical_specialty, Fetus, Lineage (genetic), Transition (genetics), business.industry, 030208 emergency & critical care medicine, Anatomy, Engrailed-1, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, medicine, Surgery, Cutaneous wound, Fibroblast, business
Published
2016
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3. Heterochronic Parabiosis Rejuvenates Aged Bones

Author

Michael T. Longaker, Owen Marecic, Michael Snyder, Irving L. Weissman, Ruth Tevlin, Charles Chan, Adrian McArdle, Taylor Wearda, Kshemendra Senarath-Yapa, and Graham G. Walmsley

Subjects
Pathology, medicine.medical_specialty, business.industry, Parabiosis, Cartilage, Bone healing, medicine.disease, Skeletal tissue, medicine.anatomical_structure, Stroma, Diabetes mellitus, Medicine, Surgery, Progenitor cell, business, Heterochrony
Abstract

INTRODUCTION: Diabetes mellitus is associated with an increased incidence of non-union, delayed union and mal-union of fractures. The mechanism(s) leading to impaired fracture healing remain to be elucidated. Recruitment of tissue stem and progenitor cells is vital to restoring injured bones. Our laboratory has recently identified a clonal precursor of bone, cartilage and stroma (BCSP) that generates mature skeletal tissue through a series of functionally characterized cellular intermediates. We hypothesize that impaired recruitment of this BCSP and its downstream progenitors contributes to poor fracture healing in diabetes.

Published
2014
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4. Identification and Targeted Inhibition of a Fibroblast Lineage Responsible for Skin Scarring and Cancer Stroma

Author

Michael T. Longaker, Zeshaan N. Maan, Michael S. Hu, Adrian McArdle, Graham G. Walmsley, Elizabeth R. Zielins, Irving L. Weissman, H. Peter Lorenz, Daniel T. Montoro, and Yuval Rinkevich

Subjects
Pathology, medicine.medical_specialty, medicine.anatomical_structure, Lineage (genetic), business.industry, medicine, Surgery, Identification (biology), Fibroblast, business, SKIN SCARRING, Cancer stroma
Published
2014
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5. Transdermal Drug Delivery of Deferoxamine Accelerates Healing and Improves Quality of Diabetic Wounds

Author

Zeshaan N. Maan, Graham G. Walmsley, Christopher R. Davis, Geoffrey C. Gurtner, Melanie Rodrigues, Arnetha J. Whitmore, Alexander J. Whittam, Jayakumar Rajadas, Dominik Duscher, and Michael S. Hu

Subjects
Deferoxamine, business.industry, Anesthesia, media_common.quotation_subject, Medicine, Surgery, Quality (business), business, medicine.drug, Transdermal, media_common
Published
2014
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7. Microfluidic single cell transcriptional analysis reveals subpopulations of adipose derived stromal cells with enhanced angiogenic potential

Author

Graham G. Walmsley, Elizabeth R. Zielins, Michael T. Longaker, Elizabeth A. Brett, Derrick C. Wan, Geoffrey C. Gurtner, Kevin J. Paik, Michael Januszyk, and Anna Luan

Subjects
Stromal cell, biology, business.industry, Cartilage, Adipose tissue, Elastic cartilage, Cell biology, Extracellular matrix, medicine.anatomical_structure, Tissue engineering, otorhinolaryngologic diseases, medicine, biology.protein, Fibrocartilage, Surgery, sense organs, business, Elastin
Abstract

INTRODUCTION: The auricular cartilage of the outer ear is composed of chondrocytes embedded in an extracellular matrix (ECM) predominated by collagen (type II), elastin, and various glycosaminoglycan macromolecules. Tissue engineered cartilage for outer ear reconstruction has several disadvantages including fibrocartilage instead of elastic cartilage and weak structural integrity. This study seeks to demonstrate the feasibility of using an Integrated Organ Printing (IOP) platform to fabricate a construct able to develop cartilage tissue in a stable 3-D shape.

Published
2015
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8. Wounds outcompete tumors for neovascularization

Author

Michael S. Hu, Robert C. Rennert, H. Peter Lorenz, Amato J. Giaccia, Zeshaan N. Maan, Graham G. Walmsley, Michael T. Longaker, Geoffrey C. Gurtner, Wan Xing Hong, and David Atashroo

Subjects
Neovascularization, Pathology, medicine.medical_specialty, business.industry, medicine, Surgery, medicine.symptom, business
Published
2015
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9. Melanoma Progression Depends on CXCL12 Expression by Host Endothelium

Author

Michael S. Hu, Arnetha J. Whitmore, Michael Januszyk, Michael T. Longaker, Alexander J. Whittam, Geoffrey C. Gurtner, Zeshaan N. Maan, Graham G. Walmsley, Dominik Duscher, and Lauren H. Fischer

Subjects
business.industry, Medicine, Surgery, business, Humanities
Abstract

Long-Term Clinical and Holistic Outcomes in Children with Cleft Lip and/or Palate: A Multidisciplinary, MixedMethods Approach Alexander C Allori, MD, MPH, Irene J Pien, Danielle L Sobol, Anna R Carlson, MD, Stephanie Watkins, MD, MSPH, Arthur S Aylsworth, MD, Robert E Meyer, PhD, Luiz Pimenta, DDS, PhD, Ronald Strauss, DMD, PhD, Jeffrey R Marcus, MD, FACS Duke University, Durham, NC, University of North Carolina, Chapel Hill, NC, Department of Health and Human Services, Raleigh, NC

Published
2015
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10. Endothelial Cell Derived Stromal-Derived Factor-1 (SDF-1) Regulates Neovascularization and Fibroblast Physiology in Response to Ischemia

Author

Alexander J. Whittam, Arnetha J. Whitmore, Michael S. Hu, Lauren H. Fischer, Graham G. Walmsley, Geoffrey C. Gurtner, Michael T. Longaker, Zeshaan N. Maan, Robert C. Rennert, and Dominik Duscher

Subjects
Neovascularization, Endothelial stem cell, Stromal cell, medicine.anatomical_structure, business.industry, Cancer research, medicine, Ischemia, Surgery, medicine.symptom, medicine.disease, business, Fibroblast
Published
2014
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11. Reduced Regenerative Capacity of Aged Adipose Derived Stem Cells is Caused by Alterations of Cell Subpopulation Dynamics

Author

Geoffrey C. Gurtner, Graham G. Walmsley, Michael T. Longaker, Zeshaan N. Maan, Robert C. Rennert, Dominik Duscher, Michael Januszyk, Alexander J. Whittam, David Atashroo, and Michael S. Hu

Subjects
medicine.anatomical_structure, business.industry, Dynamics (mechanics), Cell, Medicine, Adipose tissue, Surgery, business, Cell biology
Published
2014
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