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Catastrophic acute bilateral lower limbs necrosis associated with COVID-19 as a likely consequence of both vasculitis and coagulopathy A few cases of digital ischaemia and necrosis have also been reported in association with coagulopathy.3,4 Bellosta et al.,5 who conducted an observational study of 20 patients infected by COVID-19 and treated for acute lower limb ischaemia, suggested a higher incidence of acute limb ischaemia in COVID-19 positive patients. Characterization of acute acro-ischemic lesions in non-hospitalized patients: a case series of 132 patients during the COVID-19 outbreak. [Extracted from the article]