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Your search keyword '"Simona Osella-Abate"' showing total 4 results
Start Over Author "Simona Osella-Abate" Journal journal of the european academy of dermatology and venereology
4 results on '"Simona Osella-Abate"'

1. Age as a prognostic factor in thick and ultrathick melanomas without lymph node metastasis

Author

Joseph Malvehy, Esperanza Manrique-Silva, Antonio Tejera-Vaquerizo, Aram Boada, Carlos Ferrándiz, David Moreno-Ramírez, Sebastian Podlipnik, Juan J. Ríos-Martín, Simone Ribero, Paola Cassoni, Susana Puig, Simona Osella-Abate, Celia Requena, and Eduardo Nagore

Subjects
Oncology, medicine.medical_specialty, Prognostic factor, Skin Neoplasms, Sentinel Lymph Node Biopsy, business.industry, Melanoma, MEDLINE, Dermatology, Lymph node metastasis, Prognosis, medicine.disease, Infectious Diseases, Text mining, Lymphatic Metastasis, Internal medicine, Humans, Lymph Node Excision, Medicine, Lymph Nodes, business, Neoplasm Staging, Retrospective Studies
Published
2020

2. Relevance of multiple basin drainage and primary histologic regression in prognosis of trunk melanoma patients with negative sentinel lymph nodes

Author

M.G. Bernengo, Rebecca Senetta, Anna Sapino, Paola Savoia, Simona Osella-Abate, Martina Sanlorenzo, Pietro Quaglino, Giuseppe Macripò, Simone Ribero, and Luigia Macrì

Subjects
medicine.medical_specialty, business.industry, Melanoma, Sentinel lymph node, Retrospective cohort study, Dermatology, medicine.disease, Gastroenterology, Trunk, Surgery, Breslow Thickness, Infectious Diseases, Lymphatic system, Internal medicine, medicine, Lymph, business, Survival rate
Abstract

Background Lymphatic drainage to multiple basins (MLBD) is frequently observed in patients with primary melanoma located in the trunk. Conflicting data regarding the prognostic impact of MLBD are reported. Objective and methods We reviewed our case series of 352 patients with trunk melanoma to evaluate the pattern of basin drainage and to analyse whether different basin drainages may have different significance in negative sentinel lymph node (SLN) patients. The presence of single/multiple basin drainage, the status of SLN, the presence of melanoma regression, Breslow thickness, ulceration and type of melanoma were recorded for each patients and correlated to Disease Free Survival (DFS) and Overall Survival (OS). Results MLBD occurred in 77 patients (21.9%) and single basin lymphatic drainage (SLBD) occurred in 275 patients (79.1%). The presence of metastases in SLN was not significantly different in patients with MLBD compared to those with SLBD (26% vs. 19.6%). No differences in OS and DFS were found in SLBD/MLBD independently from SLN status. However DFS was higher in patients with MLBD and negative SLN (P = 0.0001), in addition, in patients with negative SLN and SLBD disease recurrence was 19% while was only 7% in patients with negative SLN obtained from MLBD (P = 0.03). Multivariate analysis showed that Breslow thickness

Published
2012

3. Clinical and prognostic reports from 270 patients with multiple primary melanomas: a 34-year single-institution study

Author

Mauro Novelli, Tommaso Deboli, Simona Osella-Abate, Mt Fierro, Elena Stroppiana, Federica Marenco, Paola Savoia, and M.G. Bernengo

Subjects
medicine.medical_specialty, Multivariate analysis, business.industry, Melanoma, Disease progression, Dermatology, Ajcc stage, medicine.disease, Infectious Diseases, Patient age, Epidemiology, medicine, In patient, Single institution, business, neoplasms
Abstract

Background Development of more than one primary melanoma in a sole patient is frequent, accounting for 1.2–8.2% of melanoma patients in most recent series. Objective and methods Clinical, histological and epidemiological characteristics of 270 multiple primary melanomas patients were reviewed. Results Two-hundred and seven patients (76.7%) had two melanomas, whereas in the remaining 63 the number of primary ranged from three to eight; on the whole, 639 multiple primary melanomas were identified. Synchronous melanomas developed more frequently in patients with three or more lesions; median age was significantly lower in the group of patients with more than three melanomas than in the others. Mean Breslow’s thickness significantly decreases (P

Published
2011

4. Disease progression in melanoma patients with negative sentinel lymph node: does false-negative specimens entirely account for this phenomenon?

Author

Virginia Caliendo, Giuseppe Macripò, Paolo Fava, Simona Osella-Abate, Pietro Quaglino, M.G. Bernengo, Simone Ribero, and Paola Savoia

Subjects
Oncology, medicine.medical_specialty, medicine.diagnostic_test, business.industry, Melanoma, Incidence (epidemiology), Sentinel lymph node, False Negative Reactions, Dermatology, medicine.disease, Surgery, Breslow Thickness, Infectious Diseases, Internal medicine, Biopsy, medicine, Young adult, business, Progressive disease
Abstract

Background Sentinel lymph node (SLN) status is the most important prognostic factor for subjects with primary melanoma thicker than 1 mm. Objective We focused our study on patients with disease progression after negative SLN biopsy (SLNB), with the aim of elucidating their clinical and histopathological characteristics, outcome and real incidence of false negative. Methods A total of 688 melanoma patients who underwent SLNB (1 May 1998–31 December 2008) were analysed; all patients had Breslow >1 mm or Breslow

Published
2011

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