1. Transmitted drug resistance associated with transmission clusters in newly diagnosed antiretroviral-naïve patients in Northern Greece
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Olga Tsachouridou, Lemonia Skoura, Anna-Bettina Haidich, Jean L. Mbisa, Andrew J. Buckton, Zoe A. Antoniadou, Evagelia Papadimitriou, Symeon Metallidis, D. Valagouti, Pavlos Nikolaidis, P. Kollaras, D Pilalas, N. Malisiovas, and Androniki Papoutsi
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medicine.medical_specialty ,Transmission (medicine) ,business.industry ,Public health ,Human immunodeficiency virus (HIV) ,Public Health, Environmental and Occupational Health ,Drug resistance ,Newly diagnosed ,medicine.disease ,Bioinformatics ,medicine.disease_cause ,Pharmacotherapy ,Infectious Diseases ,Acquired immunodeficiency syndrome (AIDS) ,Internal medicine ,Poster Presentation ,medicine ,Antiretroviral naive ,business - Abstract
Purpose of the study: To determine the contribution of transmission clusters on transmitted drug resistance (TDR) in newly diagnosed antiretroviral naive patients in Northern Greece, during 2000 -2007. Methods: Viral reverse transcriptase and protease genes from 369 individuals with newly diagnosed HIV-1 infection were sequenced at baseline. A maximum-likelihood phylogenetic analysis method was employed to examine for linkage between viral isolates. Clinical data were retrieved from the database and cross-referenced with the patients' medical files. Transmitted drug resistance was defined in accordance with the Surveillance Drug Resistance Mutation (SDRM) 2009 list. Supplement: Abstracts of the Tenth International Congress on Drug Therapy in HIV Infection http://www.biomedcentral.com/content/pdf/1758-2652-13-S4-info.pdf Conference: Tenth International Congress on Drug Therapy in HIV Infection 7-11 November 2010 Glasgow, UK (Published: 8 November 2010) doi:10.1186/1758-2652-13-S4-P125 Cite this article as: Skoura et al.: Transmitted drug resistance associated with transmission clusters in newly diagnosed antiretroviral-naive patients in Northern Greece. Journal of the International AIDS Society 2010 13(Suppl 4):P125. Full text: PubMed Central: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112900/
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