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Your search keyword '"Lucia Cretella"' showing total 2 results
Start Over Author "Lucia Cretella" Journal journal of the neurological sciences
2 results on '"Lucia Cretella"'

1. Neurotoxicity-related to CAR-T therapy: Proposed protocol and preliminary data from Bologna

Author

Paola Tacchetti, Giulia Amore, Luisa Sambati, Beatrice Casadei, Irene Defrancesco, Cinzia Pellegrini, Lucia Cretella, Francesco De Felice, Rita Rinaldi, Elena Zamagni, Francesca Bonifazi, Michele Cavo, Susanna Mondini, Susanna Sammali, Marianna Nicodemo, Pier Luigi Zinzani, Rossella Santoro, Elisabetta Pierucci, Pietro Cortelli, Umberto Pensato, Francesca Rondelli, Maria Guarino, and Roberto D'Angelo

Subjects
Protocol (science), Oncology, medicine.medical_specialty, Neurology, business.industry, Internal medicine, medicine, Neurotoxicity, Neurology (clinical), Car t cells, medicine.disease, business
Published
2021
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2. Cognitive and affective disorders in critical SARS-CoV-2 patients and caregivers

Author

Rossella Santoro, Tommaso Tonetti, Maria Guarino, Lucia Cretella, M. Della Giovampaola, L Mascia, P. Bottausci, Luisa Sambati, Katia Mattarozzi, Pietro Cortelli, and L. Romano

Subjects
Pediatrics, medicine.medical_specialty, business.industry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Neuropsychology, Cognition, Intensive care unit, Article, law.invention, Neurology, Quality of life, law, medicine, Verbal fluency test, Anxiety, Neurology (clinical), medicine.symptom, business, Depression (differential diagnoses)
Abstract

Background and aims: We investigated cognitive and affective disorders in patients with SARS-CoV-2 hospitalized in Intensive Care Unit (ICU). Care givers quality of life, psychological distress and satisfaction with the information received by health-care professionals were assessed. Methods: From March 1 to April 30, 2020, 22 consecutive patients with SARS-CoV-2 infection, confirmed by PCR on oronasopharyngeal swab, requiring ICU admission were recruited together with a caregiver. Patients with previous cognitive disorders were excluded. Three months after ICU discharge, patients underwent a comprehensive neuropsychological evaluation and filled out validated questionnaires. Results: Seven of 22 resulted mildly cognitively impaired. Memory was the most impaired domain, followed by attention and verbal fluency. Three out of 22 patients reported an average high level of anxiety but no depression. Quality of life was mild impaired for 19 patients. Lower performances at MoCA were related to higher APACHE score at T0 (r = −.44;p −.48;ps −.53;ps −.53;ps

Published
2021

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