25 results on '"Ouwehand W"'
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2. The epigenetic landscape of platelet and red blood cell traits: PA 2.04–2
3. Novel loci associated with glycoprotein VI expression identified by a genome-wide association study and locus-specific fine-mapping: OC 88.2
4. The ThromboGenomics Next Generation Sequencing Platform for the DNA-based diagnosis of known inherited rare bleeding and platelet disorders: OC 62.3
5. A recombinant HPA-1a antibody with abrogated Fc? receptor binding for treatment of fetomaternal alloimmune thrombocytopenia: proof of principle in human studies: OC 35.1
6. Functional characterisation of novel regulators of haematopoiesis: from GWAS to function: OC 33.3
7. Tropomyosin 4 is a novel regulator of platelet production in mice and humans: OC 33.5
8. Reactome – a curated knowledgebase of biological pathways: megakaryocytes and platelets
9. Exome sequencing identifies NBEAL2 as the causative gene for gray platelet syndrome: O-TH-141
10. Sixty-eight genetic loci uncover new gene functions in hematopoiesis and platelet formation: SY-TH-025
11. Mapping the platelet proteome: a report of the ISTH Platelet Physiology Subcommittee
12. The discovery of genes implicated in myocardial infarction
13. Overexpression of the partially activated αIIbβ3D723H integrin salt bridge mutant downregulates RhoA activity and induces microtubule-dependent proplatelet–like extensions in Chinese hamster ovary cells
14. Clustering of PECAM-1 inhibits multiple platelet signaling pathways and results in significant reduction of thrombus formation: OC-TH-093
15. Characterisation of novel platelet surface thiol isomerase enzymes: OC-TH-037
16. Platelet soluble mediators induce a monocyte gene expression profile that is anti-inflammatory, antithrombotic and pro-angiogenic: OC-WE-126
17. Increase in mRNA levels of platelet-specific genes within an arterial thrombus: OC-TU-029
18. Defining the function of novel platelet genes using a laser thrombosis model in danio rerio: AS-MO-037
19. Immunologic and structural analysis of eight novel domain-deletion β3 integrin peptides designed for detection of HPA-1 antibodies
20. Three novel β3 domain-deletion peptides for the sensitive and specific detection of HPA-4 and six low frequency β3-HPA antibodies
21. Mapping the platelet profile for functional genomic studies and demonstration of the effect size of the GP6 locus
22. Platelet genomics and the risk of atherothrombosis
23. Definition of novel GP6 polymorphisms and major difference in haplotype frequencies between populations by a combination of in-depth exon resequencing and genotyping with tag single nucleotide polymorphisms
24. Gain- and loss-of-function mutants confirm the importance of apical residues to the primary interaction of human glycoprotein VI with collagen
25. Immunologic and structural analysis of eight novel domain-deletion β3integrin peptides designed for detection of HPA-1 antibodies
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